SBIR Phase I: Large array microring resonator biosensor

SBIR 第一阶段：大阵列微环谐振器生物传感器

• 批准号: 0740552
• 负责人: Ronald Kubacki
• 金额: --
• 依托单位: IONIC SYSTEMS INC
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-01-01 至 2008-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0740552&HistoricalAwards=false
• 关键词: SBIR; Phase; Large; array; microring

This Small Business Innovation Research Phase I project will combine photonic and materials science using molecularly engineered semiconductor nanocomposites with antibody capture layers to construct high-sensitivity biosensors. The nanocomposite will be used to fabricate high?finesse, planar microring resonators in large arrays to produce high throughput biosensing arrays. The sensors will be developed to detect foodborne pathogens but create a platform that can subsequently be applied to additional health care and homeland security issues. The broader impacts of this research will be to provide biosensors that can quickly and cost effectively detect the more than 200 known diseases that are transmitted through food by viruses, bacteria, parasites, toxins, metal, and poisons. This research uses molecular engineering and nanotechnology to provide a bridge between integrated circuit (IC) and biosensing device manufacture in order to bring IC levels of improved performance and lowered cost to revolutionize biosensor availability and answer a market need, that is insuring the quality and safety of the food chain. This innovation research will address this need with a cost efficient, highly integrated optobiologic sensor array.

这个小企业创新研究第一阶段项目将结合联合收割机光子和材料科学，使用分子工程半导体纳米复合材料与抗体捕获层，以构建高灵敏度的生物传感器。纳米复合材料将用于制造高？精细，平面微型谐振器在大阵列，以产生高通量生物传感阵列。传感器将被开发用于检测食源性病原体，但创建一个平台，随后可应用于其他医疗保健和国土安全问题。这项研究的更广泛的影响将是提供生物传感器，可以快速和成本有效地检测通过病毒，细菌，寄生虫，毒素，金属和毒药通过食物传播的200多种已知疾病。这项研究使用分子工程和纳米技术在集成电路（IC）和生物传感设备制造之间架起了一座桥梁，以提高IC的性能和降低成本，从而彻底改变生物传感器的可用性，并满足市场需求，即确保食物链的质量和安全。这项创新研究将通过具有成本效益的高度集成的光生物传感器阵列来满足这一需求。