RCN: The Porphyra Genome: Promoting Resource Development and Integrative Research in Algal Genomics

RCN：紫菜基因组：促进藻类基因组学的资源开发和综合研究

• 批准号: 0741907
• 负责人: Susan Brawley
• 金额: $ 49.89万
• 依托单位: University of Maine
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2017-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0741907&HistoricalAwards=false
• 关键词: RCN; Porphyra; Genome; Promoting; Resource

This project will promote studies of the genome of an economically important red alga, Porphyra ("nori", "laver"), which is a current sequencing project at the Joint Genome Institute (DOE). Analysis of the Porphrya genome will include comparative studies with genomes of closely related and derived groups (e.g., other red algae, green algae, dinoflagellates). The overall goal of this project is to establish a network of investigators whose members will provide the highest quality public dissemination of the Porphyra genome for use by researchers worldwide, while fostering new collaborations that will lead to experimental application of the genomic data. It is anticipated that RCN-aided use of the Porphyra genome will lead to new understanding of nuclear-organelle co-evolution, studies of nitrogen and carbon metabolism in photosynthetic organisms, comparative investigations of how multicellular complexity arose independently in different eukaryotic groups, and the generation of a wealth of new markers for studies in molecular evolution and systematics. The RCN will meet annually, with continued work among participants throughout the year. Each annual meeting will include formal bioinformatics training, evaluation of the overall quality of genome annotation, and research reports and discussions on cross-genomic and experimental applications of the genomic data. The RCN will include many students and postdoctoral fellows who will form a group of genomics-competent young researchers organized around central questions that will impact key societal needs including multitrophic aquaculture (e. g., bioremediation) and an integrated analysis of photosynthetic and photoprotective pigments as they affect carbon metabolism on our warming planet. The website will include genome-related lessons for K-12 and college instructors, and the RCN will sponsor public convocations and professional symposia that will present the many contributions of the genome project while highlighting the diversity of scientists engaged in this work.

该项目将促进对经济上重要的红藻紫菜（“紫菜”、“紫菜”）基因组的研究，这是联合基因组研究所（DOE）目前的一个测序项目。对紫菜基因组的分析将包括与密切相关和衍生群体（例如，其他红藻、绿藻、鞭毛藻）的基因组进行比较研究。该项目的总体目标是建立一个研究人员网络，其成员将提供最高质量的紫菜基因组公共传播，供全球研究人员使用，同时促进新的合作，将导致基因组数据的实验应用。预计在rcn的帮助下，紫菜基因组的使用将导致对核细胞器共同进化的新认识，光合生物氮和碳代谢的研究，多细胞复杂性如何在不同真核生物群体中独立产生的比较研究，以及为分子进化和系统研究提供丰富的新标记。RCN将每年举行一次会议，参与者全年都在继续工作。每届年会将包括正式的生物信息学培训，基因组注释整体质量评估，以及基因组数据跨基因组和实验应用的研究报告和讨论。RCN将包括许多学生和博士后，他们将组成一个基因组学能力强的年轻研究人员小组，围绕将影响关键社会需求的核心问题组织起来，包括多营养水产养殖（例如，生物修复）和光合作用和光保护色素的综合分析，因为它们影响我们变暖的星球上的碳代谢。该网站将为K-12和大学教师提供与基因组相关的课程，RCN将赞助公共会议和专业研讨会，这些会议将展示基因组计划的许多贡献，同时强调从事这项工作的科学家的多样性。