Photonic Crystal Enhanced Fluorescence

光子晶体增强荧光

• 批准号: 0754122
• 负责人: Brian Cunningham
• 金额: $ 35.06万
• 依托单位: University of Illinois at Urbana-Champaign
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2013-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0754122&HistoricalAwards=false
• 关键词: Photonic; Crystal; Enhanced; Fluorescence

0754122CunninghamThe proposal describes a basic design for a 2-dimensional surface photonic crystal and shows how such a structure provides high Q-factor optical resonances with enhanced near fields at a precisely defined wavelength. Using devices designed for excitation of the fluorophore Cy5 or for semiconductor quantum dots, they propose characterization of the enhanced excitation effects spatial distribution and the design/fabrication of structures with optimal capability to take advantage of enhanced excitation through higher Q and/or redistribution of the resonant modes. They propose to characterize the enhanced extraction effect using various geometrical arrangements of the photonic crystal lattice, and the development of materials and fabrication approaches resulting in optimal signal/noise. They plan to combine label-free photonic crystal biosensor detection with enhanced fluorescence on the same surface, enabling dual-mode imaging detection that can discriminate between labeled and non-labeled analytes.

该提案描述了一种二维表面光子晶体的基本设计，并展示了这种结构如何在精确定义的波长下提供具有增强近场的高Q因子光学共振。使用为激发荧光团Cy5或半导体量子点而设计的器件，他们提出了增强激发效应的空间分布的表征，以及具有最佳能力的结构的设计/制造，以通过更高的Q和/或共振模式的重新分布来利用增强激发。他们建议利用光子晶体晶格的各种几何排列以及材料和制造方法的发展来表征增强的提取效果，从而产生最佳的信号/噪声。他们计划将无标记光子晶体生物传感器检测与同一表面上增强的荧光相结合，实现双模成像检测，可以区分标记和非标记分析物。