Photonic Crystal Enhanced Fluorescence

该提案描述了二维表面光子晶体的基本设计，并显示了这种结构如何在精确定义的波长处提供具有增强近场的高Q因子光学谐振。使用为激发荧光团Cy 5或半导体量子点而设计的器件，他们提出了增强激发效应空间分布的表征以及具有最佳能力的结构的设计/制造，以利用通过更高Q和/或共振模式的重新分布而增强的激发。他们建议使用光子晶体晶格的各种几何排列来表征增强的提取效果，以及导致最佳信号/噪声的材料和制造方法的发展。他们计划将联合收割机无标记光子晶体生物传感器检测与同一表面上的增强荧光结合起来，实现可以区分标记和非标记分析物的双模成像检测。

0754122CunninghamThe proposal describes a basic design for a 2-dimensional surface photonic crystal and shows how such a structure provides high Q-factor optical resonances with enhanced near fields at a precisely defined wavelength. Using devices designed for excitation of the fluorophore Cy5 or for semiconductor quantum dots, they propose characterization of the enhanced excitation effects spatial distribution and the design/fabrication of structures with optimal capability to take advantage of enhanced excitation through higher Q and/or redistribution of the resonant modes. They propose to characterize the enhanced extraction effect using various geometrical arrangements of the photonic crystal lattice, and the development of materials and fabrication approaches resulting in optimal signal/noise. They plan to combine label-free photonic crystal biosensor detection with enhanced fluorescence on the same surface, enabling dual-mode imaging detection that can discriminate between labeled and non-labeled analytes.