Multimode Smartphone Biosensor

智能手机生物传感器将利用内部摄像头作为光谱仪，内部LED作为宽带光源。演示的应用将包括检测用于指示儿童营养状况的生物标记蛋白，检测可能污染收获玉米的有毒化学物质，检测用于识别细菌病原体的mRNA序列，以及检测HIV病毒抗体。低成本、强大和多模式生物传感器检测能力的广泛可用性，将刺激传感应用在缺乏实验室能力或目前封闭的无数环境中的加速发展。平台只针对一个非常特定的商业市场。基于智能手机的检测系统有望在没有实验室设施的情况下找到应用，例如家庭、诊所、农场或偏远地区的即时护理分析。基于智能手机的传感器的数据共享功能将使分布式传感器网络能够部署在大范围的物理区域，但基于云的系统可以整理和绘制数据。这样的系统可以帮助解释传感器数据，或者使数据随时可供不在同一地点的临床医生使用。

1264377CunninghamThe smartphone biosensor will utilize the internal camera as a spectrometer, and the internal LED as a broadband light source. Demonstrated applications will include detection of biomarker proteins that are used to indicate the nutritional status of children, detection of a toxic chemical that can contaminate harvested corn, detection of mRNA sequences used to identify a bacterial pathogen, and detection of an HIV viral antibody. The wide availability of a low-cost, robust, and multimode biosensor detection capability will spur accelerated development of sensing applications in myriad settings where laboratory capabilities are lacking, or where current ?closed? platforms are aimed at only a very specific commercial market. Smartphone-based detection systems are expected to find applications in situations where laboratory facilities are not available such as point-of-care analysis in the home, clinic, farm, or remote locations. The data-sharing capabilities of smartphone-based sensors will enable distributed networks of sensors to be deployed across large physical areas, but with cloud-based systems that can collate and map data. Such systems can aid in the interpretation of sensor data, or make data readily available to clinicians who are not at the same location as the patient.