MRI: Acquisition of a Shared X-ray Diffractometer for Research, Education, and Training

通过这项来自主要研究仪器（MRI）项目的奖励，来自波士顿学院的Lawrence T. Scott和他的同事Amir Hoveyda将获得一台单晶x射线衍射仪，以支持各种领域的研究，包括：1)均匀、单手性碳纳米管的化学合成；2)化学合成新催化剂的设计与开发；3)与光系统II相关的仿生化学；4)脂质双层蛋白折叠；5)新型果糖1,6-双磷酸酶抑制剂的鉴定；6)络合二苯并呋喃烷类化合物的不对称合成研究；7)用于合成fDNA的融合核苷（fN）；8)用于合成的催化二硼化反应；9)催化脚手架配体；10)利用x射线晶体学提出新的化学方法。单晶x射线晶体学技术允许精确和精确地测定分子的完整三维结构，包括键的距离和角度，它提供了分子相对于邻近分子的空间排列的准确信息。这些研究将在许多领域产生影响，从合成有机和无机化学到生物兴趣系统和材料研究。该仪器将成为教学和研究的一个组成部分。

With this award from the Major Research Instrumentation (MRI) program, Lawrence T. Scott and colleague Amir Hoveyda from Boston College will acquire a single crystal X-ray diffractometer to support research in a variety of areas including: 1) chemical synthesis of uniform, single-chirality carbon nanotubes; 2) design and development of new catalysts for chemical synthesis; 3) biomimetic chemistry relevant to Photosystem II; 4) protein folding in lipid bilayers; 5) identification of new classes of inhibitors of fructose 1,6-bisphosphatase; 6) studies toward the asymmetric synthesis of complex dibenzofuranoids; 7) fused nucleosides (fN) for the synthesis of fDNA; 8) catalytic diboration reactions for use in synthesis; 9) catalytic scaffolding ligands; 10) advancing new chemical methods with X-ray crystallography.The technique of single-crystal X-ray crystallography allows accurate and precise determination of the full three dimensional structure of a molecule, including bond distances and angles, and it provides accurate information about the spatial arrangement of molecules relative to the neighboring molecules. These studies will have an impact in a number of areas ranging from synthetic organic and inorganic chemistry to systems of biological interest and materials research. This instrument will be an integral part of teaching as well as research.