MRI: Acquisition of a Flow Cytometer for Research and Teaching in Cell and Molecular Biology

MRI：购买流式细胞仪用于细胞和分子生物学的研究和教学

• 批准号: 0923533
• 负责人: Mary-Patricia Stein
• 金额: $ 27.65万
• 依托单位: The University Corporation, Northridge
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0923533&HistoricalAwards=false
• 关键词: MRI; Acquisition; Flow; Cytometer; Research

Support funds were awarded to purchase a flow cytometer for research and education. Flow cytometry is a powerful technique that allows high throughput analysis of complex biological samples. Cells can be analyzed for changes in protein expression or localization, and even ion fluxes that signify changes in cell activation or changes in cell physiology that are a prelude to cell death can be measured. The Biology Department at California State University Northridge will benefit from the acquisition of a flow cytometer in several key ways. As a Hispanic Serving Institution, CSUN plays an important role in serving the needs of students traditionally underrepresented in the sciences. Students have opportunities to engage in a variety of research programs, ranging from understanding development in model organisms such as nematodes (worms) or sea urchins to understanding the mechanisms of cell suicide (apoptosis). All faculty research enables students, both at the undergraduate and graduate level, to learn and apply their knowledge to novel and significantly important scientific questions. In addition, the incorporation of a flow cytometer in a variety of laboratory courses, including cellular physiology, neurophysiology and serology, will increase the number of students with hands-on research experience, potentially attracting and engaging students in biological inquiry that may not have otherwise been interested in careers in biology. It is anticipated that these activities will advance student learning while preparing students for their future endeavors. The outcomes from this project will include the enrollment of undergraduate and graduate students in M.S. and Ph.D. programs, the employment of students in the workforce and the publication of research articles that advance basic scientific discovery.

提供了支助资金，用于购买一台流式细胞仪，用于研究和教育。 流式细胞术是一种强大的技术，可以对复杂的生物样品进行高通量分析。可以分析细胞中蛋白质表达或定位的变化，甚至可以测量表明细胞活化变化或细胞生理学变化的离子通量，这些变化是细胞死亡的前奏。加州州立大学北岭分校的生物系将从流式细胞仪的购置中受益。 作为一个西班牙裔服务机构，CSUN在服务传统上在科学代表性不足的学生的需求发挥着重要作用。学生有机会参与各种研究项目，从了解线虫（蠕虫）或海胆等模式生物的发育到了解细胞自杀（细胞凋亡）的机制。 所有教师的研究使学生，无论是在本科和研究生阶段，学习和运用他们的知识，以新颖的和显著重要的科学问题。此外，在各种实验室课程，包括细胞生理学，神经生理学和血清学中加入流式细胞仪，将增加具有实践研究经验的学生人数，可能吸引并吸引那些可能对生物学职业不感兴趣的学生进行生物学调查。 预计这些活动将促进学生的学习，同时为学生未来的努力做好准备。 该项目的成果将包括硕士学位的本科生和研究生的入学。和博士计划，就业的学生在劳动力和研究文章的出版，推进基础科学发现。