MRI: Acquisition of a Flow Cytometer for Research and Teaching in Cell and Molecular Biology

资助资金用于购买一台流式细胞仪用于研究和教育。流式细胞术是一种强大的技术，可以对复杂的生物样品进行高通量分析。可以分析细胞中蛋白质表达或定位的变化，甚至可以测量表明细胞活化变化或细胞生理学变化的离子通量，这些变化是细胞死亡的前奏。加州州立大学北岭分校生物系将在几个关键方面受益于流式细胞仪的收购。作为一个西班牙裔服务机构，CSUN在满足传统上在科学领域代表性不足的学生的需求方面发挥着重要作用。学生有机会参与各种研究项目，从了解模式生物的发展，如线虫（蠕虫）或海胆，到了解细胞自杀（凋亡）的机制。所有学院的研究都使本科生和研究生能够学习并应用他们的知识来解决新颖和重要的科学问题。此外，将流式细胞仪纳入各种实验课程，包括细胞生理学、神经生理学和血清学，将增加有实践研究经验的学生的数量，潜在地吸引和吸引那些可能对生物学职业不感兴趣的学生。预计这些活动将促进学生的学习，同时为学生未来的努力做好准备。该项目的成果将包括招收攻读硕士和博士学位的本科生和研究生，就业学生以及发表促进基础科学发现的研究论文。

Support funds were awarded to purchase a flow cytometer for research and education. Flow cytometry is a powerful technique that allows high throughput analysis of complex biological samples. Cells can be analyzed for changes in protein expression or localization, and even ion fluxes that signify changes in cell activation or changes in cell physiology that are a prelude to cell death can be measured. The Biology Department at California State University Northridge will benefit from the acquisition of a flow cytometer in several key ways. As a Hispanic Serving Institution, CSUN plays an important role in serving the needs of students traditionally underrepresented in the sciences. Students have opportunities to engage in a variety of research programs, ranging from understanding development in model organisms such as nematodes (worms) or sea urchins to understanding the mechanisms of cell suicide (apoptosis). All faculty research enables students, both at the undergraduate and graduate level, to learn and apply their knowledge to novel and significantly important scientific questions. In addition, the incorporation of a flow cytometer in a variety of laboratory courses, including cellular physiology, neurophysiology and serology, will increase the number of students with hands-on research experience, potentially attracting and engaging students in biological inquiry that may not have otherwise been interested in careers in biology. It is anticipated that these activities will advance student learning while preparing students for their future endeavors. The outcomes from this project will include the enrollment of undergraduate and graduate students in M.S. and Ph.D. programs, the employment of students in the workforce and the publication of research articles that advance basic scientific discovery.