Tunneling Spectroscopy for Nanofabricated Biochemical Sensors

纳米生化传感器的隧道光谱

• 批准号: 0935009
• 负责人: Brian Willis
• 金额: $ 9.78万
• 依托单位: University of Connecticut
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-01-01 至 2011-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0935009&HistoricalAwards=false
• 关键词: Tunneling; Spectroscopy; Nanofabricated; Biochemical; Sensors

0601269WillisAbstractThis integrative systems proposal focuses on the science and engineering of nanofabricated molecular tunnel junctions to create novel chemical-biological sensors. The cross-departmental, interdisciplinary research program addresses the need for new concepts in low cost, portable sensing devices that can protect against environmental hazards and toxic chemical-biological agents. The research will investigate nanofabricated tunnel junctions and inelastic electron tunneling spectroscopy (IETS) for solid state sensor devices. The advantages of this work over existing concepts include: (1) sensitivity down to the single molecule level, (2) all solid state construction that allows integration into complex hybrid systems, (3) a device design that is conducive to low cost manufacturing, and (4) spectral identification of unknown molecular agents. The research will investigate a novel combination of nanofabrication techniques with atomic layer chemistry to engineer 1-2 nm spaced metal-molecule-metal tunnel junctions that will be doped with model compounds and investigated with IETS for spectral identification. The intellectual merits of the research program are the underlying science of molecular devices, including the understanding of molecule-electrode chemical interactions and charge transport through single molecule devices. In particular, there is a need for experimental data to connect physical properties and electrical measurements in single molecule tunnel junctions. IETS provides a probe of molecular structure in nanofabricated junctions that will advance the science and engineering of molecule-based devices. The broader impacts of the research program are significant for future technologies based on molecular devices that enable low cost, ubiquitous sensors that protect the public from environmental hazards and toxic chemical-biological agents. In addition, the research program will interact with the general public through a multimedia presentation to demonstrate a concrete example of nanotechnology.

0601269威利斯摘要这个综合系统的建议集中在科学和工程的纳米制造分子隧道结，创造新的化学-生物传感器。 跨部门，跨学科的研究计划解决了低成本，便携式传感设备，可以防止环境危害和有毒化学生物制剂的新概念的需求。 该研究将调查纳米制造的隧道结和非弹性电子隧穿光谱（IETS）的固态传感器设备。 与现有概念相比，这项工作的优势包括：（1）灵敏度低至单分子水平，（2）允许集成到复杂混合系统中的全固态结构，（3）有利于低成本制造的设备设计，以及（4）未知分子试剂的光谱鉴定。 该研究将研究纳米纤维技术与原子层化学的新组合，以设计1-2 nm间隔的金属-分子-金属隧道结，这些隧道结将掺杂模型化合物，并使用IETS进行光谱鉴定。 该研究计划的智力价值是分子器件的基础科学，包括对分子电极化学相互作用和通过单分子器件的电荷传输的理解。 特别是，需要实验数据来连接单分子隧道结中的物理性质和电学测量。 IETS提供了纳米制造结中分子结构的探针，这将推进基于分子的器件的科学和工程。 该研究计划的更广泛影响对于基于分子器件的未来技术具有重要意义，这些技术能够实现低成本，无处不在的传感器，保护公众免受环境危害和有毒化学生物制剂的影响。 此外，研究计划将通过多媒体演示与公众互动，以展示纳米技术的具体例子。