EFRI-BSBA: Multifunctional Materials and Devices for Distributed Actuation and Sensing

EFRI-BSBA:用于分布式驱动和传感的多功能材料和设备

基本信息

  • 批准号:
    0937985
  • 负责人:
  • 金额:
    $ 199.99万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2009
  • 资助国家:
    美国
  • 起止时间:
    2009-10-01 至 2014-09-30
  • 项目状态:
    已结题

项目摘要

EFRI-BSBA: Lepidoptera proboscises as prototypes of multifunctional fluidic devices with distributed actuation and sensingPI Name: Konstantin KornevInstitution: Clemson UniversityProposal No. 0937985 Abstract Butterflies and moths, constituting the order Lepidoptera, have inspired decades of engineering research in aerodynamics, optics, and navigation. This project focuses on the lepidopteran proboscis, which is poorly explored from an engineering perspective. The goal is to develop fundamental principles of fiber-based microfluidics inspired by the lepidopteran fluidic system, and apply these principles to the design, fabrication, and manipulation of a new class of fiber-based devices capable of transporting and probing a previously impossible range of liquids. These principles will be validated using biological data from Lepidoptera. Through collaboration of engineers, chemists, and biologists, bioinspired proboscises will be fabricated by taking advantage of modern fiber technology, which offers fiber multifunctionality such as mechanical/electromagnetic memory, improved absorbency, and controlled wettability. A biomimetic approach will be developed for actuation, sensing, and control of the synthetic proboscis. The advantages will be illustrated for an artificial proboscis to probe fluids from individual vascular smooth muscle cells. The lepidopteran fluidic system is envisioned as shifting the current microfluidic paradigm from stationary channel-like structures to fiber-based microfluidic devices, providing distributed actuation, sensing, and manipulation with minute amounts of fluids. The project will serve as a catalyst for development of novel science, engineering, and technology at the interface of biology, chemistry, materials science, and mechanical, electrical, and bioengineering. The basic principles, identified by a multidisciplinary group, will impact multiple fields, including (i) integrative biology by providing insight into the physical function of the lepidopteran fluidic system, (ii) materials science by offering new knowledge on fluid-fiber interactions and relevant fiber design parameters, (iii) robotics and control by developing biomimetic methods for shape and fluid control, and (iv) bioengineering by developing proboscis-inspired tissue-fluid probes. The basic principles can be applied to the design of a wide range of future devices, as in applications requiring low-volume fluid retrieval and analysis coupled with controlled manipulation, such as environmental monitoring and biomedical and forensic probing.
EFRI-BSBA:鳞翅目长鼻作为原型的多功能流体装置与分布式驱动和sensingPI名称:康斯坦丁Kornev机构:克莱姆森大学提案号0937985摘要蝴蝶和蛾,构成了该命令鳞翅目,激发了几十年的工程研究,在空气动力学,光学和导航。这个项目的重点是鳞翅目长鼻,这是从工程的角度探索不足。目标是开发基于纤维的微流体的基本原理,灵感来自鳞翅目流体系统,并将这些原理应用于设计,制造和操纵一类新的基于纤维的设备,这些设备能够传输和探测以前不可能的液体范围。这些原则将使用鳞翅目的生物学数据进行验证。通过工程师,化学家和生物学家的合作,将利用现代纤维技术制造生物启发的长鼻,该技术提供纤维多功能性,如机械/电磁记忆,提高吸收性和可控润湿性。一种仿生方法将被开发用于合成长鼻的驱动、传感和控制。将说明人工长鼻探测来自个体血管平滑肌细胞的流体的优点。鳞翅目流体系统被设想为将当前的微流体范例从固定的通道状结构转移到基于纤维的微流体装置,提供分布式致动、感测和操纵微量流体。该项目将作为生物学,化学,材料科学,机械,电气和生物工程接口的新科学,工程和技术发展的催化剂。由多学科小组确定的基本原理将影响多个领域,包括(i)通过提供对鳞翅目流体系统物理功能的洞察力的综合生物学,(ii)通过提供关于流体-纤维相互作用和相关纤维设计参数的新知识的材料科学,(iii)通过开发用于形状和流体控制的仿生方法的机器人和控制,以及(iv)通过开发受长鼻启发的组织流体探针进行生物工程。这些基本原理可以应用于未来各种设备的设计,例如需要低容量流体回收和分析以及受控操作的应用,例如环境监测和生物医学和法医探测。

项目成果

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Konstantin Kornev其他文献

Thermodynamic Instability of A Self-Assembled 16-Residue Alanine-Based Oligopeptide in Aqueous Media: Hydrogel, Fibril, and Beaded Filament Formation
  • DOI:
    10.1016/j.bpj.2009.12.1366
  • 发表时间:
    2010-01-01
  • 期刊:
  • 影响因子:
  • 作者:
    Thomas J. Measey;Konstantin Kornev;Reinhard Schweitzer-Stenner
  • 通讯作者:
    Reinhard Schweitzer-Stenner
Conformational Instability, Aggregation, and Hydrogel formation of a 16-Residue Alanine-Based Peptide in Aqueous Media
  • DOI:
    10.1016/j.bpj.2008.12.369
  • 发表时间:
    2009-02-01
  • 期刊:
  • 影响因子:
  • 作者:
    Thomas J. Measey;Melinda Bendon;Reinhard Schweitzer-Stenner;Guoliang Yang;Konstantin Kornev
  • 通讯作者:
    Konstantin Kornev

Konstantin Kornev的其他文献

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{{ truncateString('Konstantin Kornev', 18)}}的其他基金

Comparative Biomechanics of Hawk Moths with Minute to Giant Proboscises and Diverse Feeding Habits
具有微小到巨大喙和不同摄食习性的天蛾的生物力学比较
  • 批准号:
    2042937
  • 财政年份:
    2021
  • 资助金额:
    $ 199.99万
  • 项目类别:
    Standard Grant
Biomechanicsof Self-Assembly of the Lepidopteran Feeding Device
鳞翅目摄食装置自组装的生物力学
  • 批准号:
    1305338
  • 财政年份:
    2013
  • 资助金额:
    $ 199.99万
  • 项目类别:
    Standard Grant
Design and Surface Engineering of Nanofiber-based Probes
纳米纤维探针的设计和表面工程
  • 批准号:
    0826067
  • 财政年份:
    2008
  • 资助金额:
    $ 199.99万
  • 项目类别:
    Standard Grant

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  • 批准号:
    1112579
  • 财政年份:
    2011
  • 资助金额:
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    2010
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    $ 199.99万
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    $ 199.99万
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    2009
  • 资助金额:
    $ 199.99万
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    2009
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    0937997
  • 财政年份:
    2009
  • 资助金额:
    $ 199.99万
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    Standard Grant
EFRI-BSBA: Second Window
EFRI-BSBA:第二个窗口
  • 批准号:
    0937710
  • 财政年份:
    2009
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    $ 199.99万
  • 项目类别:
    Standard Grant
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EFRI-BSBA:用于传感和理解纳米级亚细胞结构的光子技术
  • 批准号:
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  • 财政年份:
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