MRI: Acquisition of a MALDI TOF-TOF Mass Spectrometer

该奖项由化学系和主要研究仪器(MRI)计划共同资助，佛罗里达大学的Daniel R.Talham教授及其同事John R.Reynolds、K.B.Wagener和Stephen A.Miller以及中佛罗里达大学的Kevin D.Belfield将获得基质辅助激光解吸电离串联飞行时间质谱仪(MALDI TOF-TOF MS)。该奖项将加强所有级别的研究、培训和教育，特别是在聚合物科学、化学成像、生物标记物发现和天然产品研究方面。将要研究的具体领域包括精密烯烃的非环二烯歧化研究、多光子吸收超分子光子材料、生物可降解塑料、共轭供体-受体聚合物、基于多肽的天然产物以及基于适体的平台的生物分析应用。质谱仪(MS)用于通过测量样品中的分子组成的质量来识别样品的化学成分，样品被电离并由质谱仪检测。基质辅助激光解吸电离(MALDI)是一种在将样品注入质谱仪之前用激光电离样品的技术。飞行时间(TOF)质谱仪具有高灵敏度和高质量准确度，可帮助分析和解释结果数据。这种开放获取工具将在佛罗里达大学和佛罗里达中部大学向所有人开放，并作为服务提供给整个东南部和波多黎各的外部用户群体，包括佛罗里达农工大学的几个用户群体。它将为本科生、研究生和博士后提供最先进的质谱学使用方面的培训。

With this award co-funded by the Division of Chemistry and the Major Research Instrumentation (MRI) program, Professor Daniel R. Talham and colleagues John R. Reynolds, K. B. Wagener and Stephen A. Miller from the University of Florida and Kevin D. Belfield of the University of Central Florida will acquire a matrix-assisted laser desorption ionization tandem time-of-flight mass spectrometer (MALDI TOF-TOF MS). The award will enhance research, training and education at all levels, especially in polymer science, chemical imaging, biomarker discovery and natural products research. Specific areas of research to be investigated include studies of acyclic diene metathesis of precision olefins, multiphoton absorbing supramolecular photonic materials, biodegradable plastics, conjugated donor-acceptor polymers, peptide-based natural products, and bioanalytical applications of aptamer-based platforms. Mass spectrometers (MS) are used to identify the chemical composition of a sample by measuring the mass of the molecular constituents in the sample after they are ionized and detected by the mass spectrometer. Matrix-assisted laser desorption ionization (MALDI) is a technique for preparing the sample to be ionized by a laser before injection into the mass spectrometer. The time of flight (TOF) mass analyzer has high sensitivity and mass accuracy to assist the analyses and interpretation of the resultant data. This open access instrument will be available to all at the Universities of Florida and Central Florida and as a service for external user groups throughout the Southeast and Puerto Rico, including several at Florida A&M University. It will provide training to undergraduate, graduate and post doctoral students in state-of-the-art mass spectrometry usage.