Collaborative Research: Three-Dimensional Flow-Structure Interaction During Phonation

合作研究：发声过程中的三维流-结构相互作用

• 批准号: 1067286
• 负责人: James Doyle
• 金额: $ 6.3万
• 依托单位: Purdue University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-15 至 2014-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1067286&HistoricalAwards=false
• 关键词: Collaborative; Research; Three; Dimensional; Flow

1066962/1067286Luo/DoyleVoice production is a result of the flow-structure interaction process in the larynx during which the glottal airflow causes the vocal fold tissue to vibrate more than 100 times per second. The objective of this research is to develop an accurate and yet efficient numerical approach to model the flow-induced vocal fold vibration and quantify the three-dimensional characteristics of the glottal flow and vocal fold dynamics. The numerical method will be based on an immersed-boundary method for incompressible flows with complex/moving boundaries and a nonlinear finite-element method capable of representing large deformations of soft materials. Idealized geometry of the larynx will be adopted to simply the problem and to capture the key elements of the biophysics. Several important factors including the layered tissue structure, hyperelastic tissue behavior, large tissue strains, and vocal fold impact, will be incorporated to produce a realistic model. Both the glottal flow and vocal fold vibration are highly three-dimensional, and their intriguing characteristics largely determine the unique features of an individual's voice (e.g., a soprano or tenor). The proposed research will reveal the underlying mechanisms that lead to the significant variations in the laryngeal dynamics. Specifically, the vortical structures in the flow, the oscillation mode of the vocal folds, and the impact stress on the vocal fold surface will be studied, and the effects of the laryngeal geometry and material properties of the tissue will be quantified. The conclusion drawn from the research will provide a much clearer understanding of the biophysics of phonation and will generate important guidelines for the future development of more advanced models useful in the clinical treatment of voice disorders. In addition, the flow field data produced in the numerical simulations can be used directly in the acoustic analysis of sound production in the larynx. To enrich the education of graduate and undergraduate students, a computational course incorporating multiphysics modeling will be created, which will address the interaction of fluids, thermal, structures, and electricity. Interactive online learning modules will be developed to reach out to K-12 students for them to learn interesting applications of fluid dynamics.

1066962/1067286 Luo/Doyle声音的产生是喉中流动-结构相互作用过程的结果，在此过程中，声门气流导致声带组织每秒振动超过100次。 本研究的目的是开发一种精确而有效的数值方法来模拟气流引起的声带振动，并量化声门流和声带动力学的三维特征。 数值方法将基于用于具有复杂/移动边界的不可压缩流的浸没边界方法和能够表示软材料大变形的非线性有限元方法。 喉的理想几何形状将被采用来简化问题并捕获生物物理学的关键要素。 几个重要的因素，包括分层组织结构，超弹性组织行为，大的组织应变，声带的影响，将被纳入产生一个现实的模型。 声门气流和声带振动都是高度三维的，它们的有趣特征在很大程度上决定了个体声音的独特特征（例如，女高音或男高音）。 这项研究将揭示喉动力学显著变化的潜在机制。 具体而言，将研究流动中的旋涡结构、声带的振荡模式和声带表面上的冲击应力，并量化喉部几何形状和组织材料特性的影响。 从研究中得出的结论将提供一个更清晰的了解发声的生物物理学，并将产生重要的指导方针，为未来开发更先进的模型，用于语音障碍的临床治疗。 此外，在数值模拟中产生的流场数据可以直接用于喉部发声的声学分析。 为了丰富研究生和本科生的教育，将创建一个包含多物理场建模的计算课程，该课程将解决流体，热，结构和电的相互作用。 将开发互动在线学习模块，以接触K-12学生，让他们学习流体动力学的有趣应用。