MRI: Acquisition of a High-resolution Multi-material Printing System

MRI:购置高分辨率多材料打印系统

基本信息

  • 批准号:
    1126382
  • 负责人:
  • 金额:
    $ 25.07万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2011
  • 资助国家:
    美国
  • 起止时间:
    2011-09-01 至 2013-08-31
  • 项目状态:
    已结题

项目摘要

The objective of this proposal is to obtain support for the purchase of a state-of-the-art, ultra-high-resolution, 3-dimensional printing system for rapid prototyping and rapid manufacturing of parts with complex shapes and complicated material properties. The printing system will find its primary use in the activities of the Tufts University biomechanics, biology and biomedical engineering groups. The term "rapid prototyping" refers to the automated construction of physical objects directly from computer aided design or animation software. A variety of competing rapid prototyping technologies are now commercially available. However, for our purposes, the least costly, easiest to use, fastest and most flexible technology in terms of the variety of different materials that can be processed to fabricate parts is 3-dimensional printing. In this approach, photopolymer liquids are forced through inkjet print heads to create the layers of the part, which then are cured and fused together by ultraviolet light. The printing system will be the centerpiece of a biomimetic biomechanics facility, in which it will be used to fabricate essential parts that are the basis of the research activities of the Tufts University biomechanics group, and that cannot be produced by any other method. Use of this printing system in our interdisciplinary approach to biomechanics will lead to (1) major breakthroughs in the understanding of biologic mechanical systems and (2) novel applications of biologically inspired principles to engineer mechanical devices and systems. A particularly novel aspect of this work is that we seek to understand the role of tissue material properties in living movements and to exploit materials to show similar properties to design, build and control devices emulating biologic mechanical systems. Thus acquisition of the printing system will significantly advance the field of biomechanics, by providing a crucial part of the key instrumentation used in a novel and innovative, biologically inspired, closed loop research and design facility.By allowing the fabrication of complex parts with advanced, non-uniform material properties, acquisition of the 3D printing system will permit us to undertake a large set of projects that are presently not possible due to part fabrication limitations. These projects will be central to the biomimetic biomechanics facility, allowing us to design and fabricate novel biomimetic devices and systems. Development of such devices and systems can in due course significantly impact understanding of biomechanical systems and thereby underlie new biologically inspired research and design approaches. Furthermore, the proposed project will permit the PIs to continue to engage undergraduate as well as graduate students in our ongoing research efforts, expanding the research training, educational experience and opportunities available to the students involved. Moreover, formal courses in which the printing system will be used have been identified from the Tufts Departments of Biology, Biomedical and Mechanical Engineering, and the Tufts Gordon Institute. In addition, as part of the process of recruitment of students into our projects, full attention will be given to the infrastructure in place at Tufts for recruiting and retaining women and underrepresented minorities in research. These include the New England Board of Higher Education Excellence through Diversity Program, a major forum for recruitment of underrepresented minority students, and formal ongoing outreach programs in Computer Science, Biomedical Engineering and robotics, as well as the Tufts School of Medicine NIH-funded minority outreach program, which has been highly successful in attracting underrepresented undergraduate students to summer internships for the last ten years.
该提案的目的是为购买最先进的超高分辨率三维打印系统提供支持,用于快速成型和快速制造具有复杂形状和复杂材料特性的零件。该打印系统将主要用于塔夫茨大学生物力学、生物学和生物医学工程小组的活动。术语“快速原型”是指直接从计算机辅助设计或动画软件中自动构建物理对象。各种相互竞争的快速原型技术现在已经商业化。然而,就我们的目的而言,就可以加工制造零件的各种不同材料而言,成本最低、最容易使用、最快和最灵活的技术是三维打印。在这种方法中,光聚合物液体被强制通过喷墨打印头来创建零件的层,然后通过紫外线固化和融合在一起。打印系统将成为仿生生物力学设施的核心,它将被用来制造塔夫茨大学生物力学小组研究活动的基础部件,而这些部件是任何其他方法都无法生产的。在我们的跨学科生物力学方法中使用这种打印系统将导致(1)对生物机械系统的理解取得重大突破;(2)在设计机械设备和系统时,生物学启发原理的新应用。这项工作的一个特别新颖的方面是,我们试图理解组织材料特性在生物运动中的作用,并利用材料来展示类似的特性来设计、建造和控制模拟生物机械系统的设备。因此,获得该打印系统将大大推进生物力学领域,提供用于新颖和创新的、受生物学启发的、闭环研究和设计设施的关键仪器的关键部分。通过允许制造具有先进,非均匀材料特性的复杂部件,获得3D打印系统将使我们能够承担大量目前由于部件制造限制而不可能完成的项目。这些项目将成为仿生生物力学设施的核心,使我们能够设计和制造新颖的仿生设备和系统。这些设备和系统的发展可以在适当的时候显著影响对生物力学系统的理解,从而成为新的生物学启发研究和设计方法的基础。此外,拟议的项目将允许pi继续吸引本科生和研究生参与我们正在进行的研究工作,扩大研究培训,教育经验和为参与的学生提供的机会。此外,塔夫茨大学生物系、生物医学和机械工程系以及塔夫茨戈登研究所已经确定了将使用印刷系统的正式课程。此外,作为我们项目招募学生过程的一部分,我们将充分关注塔夫茨大学为招募和留住女性和研究中代表性不足的少数民族而建立的基础设施。其中包括新英格兰高等教育卓越委员会多元化计划,这是一个招募代表性不足的少数族裔学生的主要论坛,以及计算机科学,生物医学工程和机器人技术方面的正式外展计划,以及美国国立卫生研究院资助的塔夫茨医学院少数族裔外展计划,该计划在过去十年中非常成功地吸引了代表性不足的本科生参加暑期实习。

项目成果

期刊论文数量(0)
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会议论文数量(0)
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Robert White其他文献

Perspectives from the Field: Watershed Planning and Climate Change Adaptation in the Intermountain Western United States: Linking Global Trends to Local Management
实地视角:美国西部山间流域规划和气候变化适应:将全球趋势与当地管理联系起来
  • DOI:
    10.1017/s1466046611000056
  • 发表时间:
    2011
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Carolyn J. Browning;M. Wilson;T. Cech;Robert White
  • 通讯作者:
    Robert White
O20 - Engineering of macaque CD4+ T cells and CD34+ hematopoietic stem cells resistant to <em>in vitro</em> SIV infection using zinc finger nucleases
  • DOI:
    10.1016/s2055-6640(20)31124-9
  • 发表时间:
    2016-05-01
  • 期刊:
  • 影响因子:
  • 作者:
    Peter Lentz;Gregory Bonello;Fuchun Zhou;Mary Salas;Magdalena Cepeda;Robert White;Marie-Claire Gauduin
  • 通讯作者:
    Marie-Claire Gauduin
UV-A in the NICU: New Technology for an Old Challenge
NICU 中的 UV-A:应对旧挑战的新技术
  • DOI:
    10.51362/neonatology.today/202071571724
  • 发表时间:
    2020
  • 期刊:
  • 影响因子:
    0
  • 作者:
    J. Brons;Robert White;M. Rea
  • 通讯作者:
    M. Rea
TCTracer: Establishing test-to-code traceability links using dynamic and static techniques
TCTracer:使用动态和静态技术建立测试到代码的可追溯性链接
McMaster at 50: lessons learned from five decades of PBL
  • DOI:
    10.1007/s10459-019-09908-2
  • 发表时间:
    2019-08-27
  • 期刊:
  • 影响因子:
    3.300
  • 作者:
    Alan Neville;Geoff Norman;Robert White
  • 通讯作者:
    Robert White

Robert White的其他文献

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{{ truncateString('Robert White', 18)}}的其他基金

Imaging functional chromatin architecture in Drosophila
果蝇功能性染色质结构成像
  • 批准号:
    BB/S00758X/1
  • 财政年份:
    2019
  • 资助金额:
    $ 25.07万
  • 项目类别:
    Research Grant
Manipulation of tRNA to Enhance Biologic Production
操纵 tRNA 以增强生物制品生产
  • 批准号:
    BB/S018727/1
  • 财政年份:
    2019
  • 资助金额:
    $ 25.07万
  • 项目类别:
    Research Grant
A Combinatorial Approach to Enhance Production of Monoclonal Antibodies
提高单克隆抗体产量的组合方法
  • 批准号:
    BB/M018237/1
  • 财政年份:
    2015
  • 资助金额:
    $ 25.07万
  • 项目类别:
    Research Grant
Reading the genome: how do transcription factors achieve target specificity?
读取基因组:转录因子如何实现目标特异性?
  • 批准号:
    BB/M007081/1
  • 财政年份:
    2015
  • 资助金额:
    $ 25.07万
  • 项目类别:
    Research Grant
Functional analysis of the Epstein Barr virus nuclear antigen leader protein (EBNA-LP) in a viral context.
病毒背景下 Epstein Barr 病毒核抗原前导蛋白 (EBNA-LP) 的功能分析。
  • 批准号:
    MR/L008432/1
  • 财政年份:
    2014
  • 资助金额:
    $ 25.07万
  • 项目类别:
    Research Grant
Monitoring Magmatism and Intrusion from the Bardabunga Volcano, Iceland
监测冰岛巴达本加火山的岩浆活动和入侵
  • 批准号:
    NE/M017427/1
  • 财政年份:
    2014
  • 资助金额:
    $ 25.07万
  • 项目类别:
    Research Grant
Digging for Metabolic Fossils in Methanocaldococcus Jannaschii
挖掘甲烷球菌 Jannaschii 的代谢化石
  • 批准号:
    1120346
  • 财政年份:
    2012
  • 资助金额:
    $ 25.07万
  • 项目类别:
    Continuing Grant
Interaction of Tectonics and Magmatism in the Askja spreading segment of Iceland
冰岛阿斯贾扩张段构造与岩浆作用的相互作用
  • 批准号:
    NE/H025006/1
  • 财政年份:
    2011
  • 资助金额:
    $ 25.07万
  • 项目类别:
    Research Grant
[ENERGY] Rupture properties from microseismic data
[能源] 微震数据的破裂特性
  • 批准号:
    NE/I018263/1
  • 财政年份:
    2011
  • 资助金额:
    $ 25.07万
  • 项目类别:
    Training Grant
Tracking melt injection under the Mid-Atlantic Rift near Askja, central Iceland
追踪冰岛中部阿斯贾附近大西洋中裂谷下的熔体注入
  • 批准号:
    NE/F011407/1
  • 财政年份:
    2008
  • 资助金额:
    $ 25.07万
  • 项目类别:
    Research Grant

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