Enforced Stacking of Shape-Persistent Macrocycles: A Molecular Approach for Tuning the Structures and Functions of Nanotubular Assemblies

形状持久大环化合物的强制堆积：调节纳米管组件结构和功能的分子方法

• 批准号: 1306326
• 负责人: Bing Gong
• 金额: $ 48万
• 依托单位: SUNY at Buffalo
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2017-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1306326&HistoricalAwards=false
• 关键词: Enforced; Stacking; Shape; Persistent; Macrocycles

In this project funded by the Macromolecular, Supramolecular and Nanochemistry Program of the Chemistry Division, Bing Gong of the State University of New York at Buffalo and Xiao Cheng Zeng of the University of Nebraska at Lincoln will develop a general strategy for the controlled synthesis and assembly of shape-persistent macrocyclic molecules into functional organic nanotubes containing sub-nanometer pores. Because the interior and exterior of the macrocycles may be functionalized independently, both the diameters and inner surfaces of the nanopores may be modified in a controlled manner. The nanopores, eventually, will be incorporated into membranes and allow for the selective transport of water across the membrane. The broader impacts involve cross-disciplinary training of graduate and undergraduate students, incorporating research into teaching, outreach to students at primarily undergraduate institutions, and the potential long term impacts of water purification technology. Pores of various diameters are found in a range of synthetic and natural objects. For example, water purification technologies utilize porous membranes that permit the selective passage of water over the other salt and organic components. In biology, cell membranes contain protein pore structures that select for the transport of specific molecules and ions and contain active functions that are far more advanced than synthetic pores. This research project will enhance our understanding of how to prepare and assemble molecules into pores that permit the transport of one type of molecule, such as water. The research will impact our fundamental knowledge of chemistry in this area, yet may have direct application to various technologies that utilize porous materials, such as water purification. This project also will provide mechanisms to educate undergraduate and graduate at the frontiers and interfaces of molecular, biological, and physical sciences.

在这个由化学系大分子、超分子和纳米化学项目资助的项目中，布法罗的纽约州立大学的龚兵和内布拉斯加大学林肯分校的曾晓成将开发一种控制合成和组装形状持久的大环分子到含有亚纳米孔的功能性有机纳米管中的一般策略。因为大环的内部和外部可以独立地官能化，所以纳米孔的直径和内表面都可以以受控的方式改性。最终，纳米孔将被纳入膜中，并允许水选择性地穿过膜。 更广泛的影响涉及研究生和本科生的跨学科培训，将研究纳入教学，主要是本科院校的学生推广，以及水净化技术的潜在长期影响。在一系列合成和天然物体中发现了各种直径的孔隙。 例如，水净化技术利用多孔膜，其允许水相对于其他盐和有机组分选择性地通过。 在生物学中，细胞膜包含蛋白质孔结构，其选择用于特定分子和离子的运输，并且包含远比合成孔先进的活性功能。 这个研究项目将提高我们对如何制备和组装分子到允许运输一种类型的分子（如水）的孔中的理解。 这项研究将影响我们在这一领域的化学基础知识，但可能直接应用于利用多孔材料的各种技术，如水净化。 该项目还将提供机制，在分子，生物和物理科学的前沿和界面教育本科生和研究生。