EAGER: The First Steps toward Crosslinked Membranes with Non-Collapsible, Uniform Pores of Sub-nanometer Size: Synthesis of Building Blocks and Alignment of Nanotubular Assemblies

EAGER：迈向具有亚纳米尺寸的不可塌陷、均匀孔隙的交联膜的第一步：构建块的合成和纳米管组件的排列

• 批准号: 1036171
• 负责人: Bing Gong
• 金额: $ 15万
• 依托单位: SUNY at Buffalo
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-15 至 2012-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1036171&HistoricalAwards=false
• 关键词: EAGER; First; Steps; toward; Crosslinked

This one-year EAGER award addresses the early stage fabrication of nanoporous membranes containing non-deformable pores with a uniform, subnanometer size. The resultant membranes will be used for water purification and desalination, as well as other size- and property-dependent molecular separations. The primary focus will be the use of a highly efficient, one-pot synthetic method for preparing large amount of macrocyclic building blocks that will then be used for engineering the membranes. The building blocks are macrocycles sharing a rigidified, cyclic backbone that contain a non-collapsible hydrophilic cavity of ~5-6 angstroms. Recent studies indicate that this class of macrocycles have a high propensity to associate into 1D tubular assemblies. Based on preliminary results, analogous macrocycles with side chains carrying polar terminal groups should self-assemble into nanoporous membranes. The alignment of the 1D tubular assemblies in the capillary pores of anodic alumina membranes will be probed. Computer simulation will be performed to investigate transport (nanofluidic) behavior of water within the nanopore under different external pressures and to evaluate the permeability of the membrane to various ionic species in a solvent as a function of size of nanopores. Optimally designed membranes are expected to reject most small molecules and ions and will be assessed as nanofiltration membranes for water desalination. The proposed research is highly interdisciplinary. Graduate and undergraduate students of various backgrounds will gain skills in multiple fields involving chemistry, materials science and the engineering of corresponding molecules and devices. Specifically, the educational impacts of this joint research include: (1) The unique opportunity to combine computer-aided design, synthesis, and characterization of molecular, supramolecular, and nanosized structures with the engineering of the corresponding materials and devices in the training of graduate students. (2) The program will involve undergraduate students, particularly those from groups traditionally underrepresented in sciences and students, who have limited exposure and access to the latest developments in the corresponding fields. (3) The research results will not only be published in highly visible journals to broadly disseminate this work to scientific society at large, but more importantly, will lead to many practical applications. Insights obtained from the construction of nanosized building blocks and the assessment of their 1D assembly will in turn will help the development of concepts generally useful for addressing other problems in the field of chemical and biological separation.

这个为期一年的EAGER奖致力于纳米多孔膜的早期制造，该膜包含具有均匀亚纳米尺寸的不可变形孔。由此产生的膜将用于水的净化和脱盐，以及其他大小和性质依赖的分子分离。主要的焦点将是使用一种高效的一锅合成方法来制备大量的大环结构单元，然后将其用于工程膜。结构单元是共享刚性环状骨架的大环，其含有约5-6埃的不可塌陷的亲水性空腔。最近的研究表明，这类大环化合物有很高的倾向，以配合成1D管状组件。基于初步的结果，类似的大环与侧链携带极性端基应自组装成纳米多孔膜。一维管状组件在阳极氧化铝膜的毛细孔的对齐将被探测。将进行计算机模拟以研究在不同外部压力下纳米孔内的水的传输（纳米流体）行为，并评估膜对溶剂中的各种离子物质的渗透性作为纳米孔尺寸的函数。 最佳设计的膜预计将拒绝大多数小分子和离子，并将被评估为用于水脱盐的纳滤膜。拟议的研究是高度跨学科的。 不同背景的研究生和本科生将获得涉及化学，材料科学和相应分子和设备工程的多个领域的技能。具体而言，这项联合研究的教育影响包括：（1）独特的机会，联合收割机结合计算机辅助设计，合成和表征的分子，超分子和纳米结构与工程的相应材料和设备的研究生的培训。(2)该计划将涉及本科生，特别是那些传统上在科学和学生中代表性不足的群体，他们接触和接触相应领域的最新发展有限。(3)研究成果不仅将发表在高知名度的期刊上，向整个科学社会广泛传播这项工作，更重要的是，将导致许多实际应用。从构建纳米级构建块和评估其1D组装获得的见解反过来将有助于开发通常用于解决化学和生物分离领域中的其他问题的概念。