CAREER: Deterministic and stochastic transport of suspended particles in periodic systems: fundamentals and applications in separation sciences.

0954840 Drazer研究目标是开发一个综合的研究和教育计划，致力于调查在空间周期性系统中悬浮颗粒运动中出现的复杂传输现象，以及将这些现象转化为流体设备中悬浮颗粒操纵的新原理。本研究的目的是建立一个统一的描述单个粒子在单相和两相空间周期性体系中的确定性和随机性输运的理论模型，为合理设计新型微流控分离装置提供基础，从而超越宏观方法的小型化，充分利用小尺度下的主导物理现象，例如布朗运动和胶体表面相互作用。为了利用这些复杂的现象，我们将利用当前制造技术提供的上级控制来确定平面微流体器件的几何结构和表面化学。该策略是创建特定的周期性模式，通过诱导对单个物种的空间分区和/或控制非线性流体动力学效应，和/或通过创建选择性的表面颗粒相互作用和/或通过引导它们的布朗运动，决定悬浮颗粒的行为。在这个项目中，我们调查了一个具有挑战性的问题，在该地区的传输现象的颗粒系统。也就是说，理解具有各向异性和非均匀性的周期性系统中悬浮胶体的确定性和随机行为。对这一领域的贡献可能会影响到广泛的学科，从更好地了解地下水库中污染物的胶体增强运输，到在传统的分析方法，如体积平均技术方面取得进展。这一成果也将影响到芯片实验室的发展领域，芯片实验室有望通过提供操纵悬浮物质的新方法而彻底改变化学科学。该项目将把研究和教育与基于网络的微流控设备中颗粒传输虚拟实验的发展结合起来。这些实验室将为用户提供一个令人兴奋的视角，让他们了解工程领域的最新发展。与此同时，这些实验室将提供一个平台来理解传输现象中的关键概念。研究和教育之间的整合的第二个方面是设计简单的实验，演示控制微流体系统中的传输的基本现象，但在宏观尺度上。具体来说，我们正在开发的实验，在平面，透明的，周期性的多孔介质制成的乐高零件的钢球的沉降。

0954840DrazerThe research goal is to develop an integrated research and education program dedicated to investigate the complex transport phenomena that arises in the motion of suspended particles in spatially periodic systems, as well as the translation of these phenomena into new principles for the manipulation of suspended particles in fluidic devices. The objective is to develop a unified description of the deterministic and stochastic transport of individual particles as they move through spatially periodic systems in both single phase and two phase systems.The proposed fundamental studies will provide the foundations for the rational design of novel microfluidic separation devices, that go beyond the miniaturization of macroscopic methods, and fully exploit the dominant physical phenomena at small scales, such as Brownian motion and colloid surface interactions. To harness these complex phenomena we will take advantage of the superior control provided by current fabrication techniques to determine the geometrical structure and surface chemistry of planar microfluidic devices. The strategy is to create specific periodic patterns that dictate the behavior of the suspended particles by inducing spatial partitioning on individual species and/or controlling non linear hydrodynamic effects, and/or by creating selective surface-particle interactions and/or by directing their Brownian motion. In this project we investigate a challenging problem in the area of transport phenomena in particulate systems. That is, understanding the deterministic and stochastic behavior of suspended colloids in periodic systems that have anisotropic and heterogeneous properties. Contributions to this field could impact a broad range of disciplines, from a better understanding of colloid enhanced transport of pollutants in underground water reservoirs, to making progress in traditional analytical methods such as volume averaging techniques. The results will also impact the growing area of lab on a chip devices, which promises to revolutionize the chemical sciences, by providing novel methods to manipulate suspended species.The project will integrate research and education with the development of web based virtual experiments on particle transport in microfluidic devices. The labs will give the users an exciting look into state of the art developments in engineering. At the same time, the labs will provide a platform to understand key concepts in transport phenomena. A second aspect of the integration between research and education is the design of simple experiments that demonstrate the fundamental phenomena that control the transport in microfluidic systems, but at a macroscopic scale. Specifically, we are developing experiments on the sedimentation of steel balls in planar, transparent, periodic porous media fabricated from LEGO pieces.