CAREER: Deterministic and stochastic transport of suspended particles in periodic systems: fundamentals and applications in separation sciences.

职业：周期性系统中悬浮颗粒的确定性和随机传输：分离科学的基础知识和应用。

• 批准号: 0954840
• 负责人: German Drazer
• 金额: $ 41.5万
• 依托单位: Johns Hopkins University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-01-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0954840&HistoricalAwards=false
• 关键词: CAREER; Deterministic; stochastic; transport; suspended

0954840DrazerThe research goal is to develop an integrated research and education program dedicated to investigate the complex transport phenomena that arises in the motion of suspended particles in spatially periodic systems, as well as the translation of these phenomena into new principles for the manipulation of suspended particles in fluidic devices. The objective is to develop a unified description of the deterministic and stochastic transport of individual particles as they move through spatially periodic systems in both single phase and two phase systems.The proposed fundamental studies will provide the foundations for the rational design of novel microfluidic separation devices, that go beyond the miniaturization of macroscopic methods, and fully exploit the dominant physical phenomena at small scales, such as Brownian motion and colloid surface interactions. To harness these complex phenomena we will take advantage of the superior control provided by current fabrication techniques to determine the geometrical structure and surface chemistry of planar microfluidic devices. The strategy is to create specific periodic patterns that dictate the behavior of the suspended particles by inducing spatial partitioning on individual species and/or controlling non linear hydrodynamic effects, and/or by creating selective surface-particle interactions and/or by directing their Brownian motion. In this project we investigate a challenging problem in the area of transport phenomena in particulate systems. That is, understanding the deterministic and stochastic behavior of suspended colloids in periodic systems that have anisotropic and heterogeneous properties. Contributions to this field could impact a broad range of disciplines, from a better understanding of colloid enhanced transport of pollutants in underground water reservoirs, to making progress in traditional analytical methods such as volume averaging techniques. The results will also impact the growing area of lab on a chip devices, which promises to revolutionize the chemical sciences, by providing novel methods to manipulate suspended species.The project will integrate research and education with the development of web based virtual experiments on particle transport in microfluidic devices. The labs will give the users an exciting look into state of the art developments in engineering. At the same time, the labs will provide a platform to understand key concepts in transport phenomena. A second aspect of the integration between research and education is the design of simple experiments that demonstrate the fundamental phenomena that control the transport in microfluidic systems, but at a macroscopic scale. Specifically, we are developing experiments on the sedimentation of steel balls in planar, transparent, periodic porous media fabricated from LEGO pieces.

0954840Drazer研究目标是开发一个综合研究和教育项目，致力于研究空间周期系统中悬浮颗粒运动中出现的复杂传输现象，以及将这些现象转化为流体装置中悬浮颗粒操纵的新原理。其目标是对单个粒子在单相和两相系统中穿过空间周期系统时的确定性和随机传输进行统一描述。所提出的基础研究将为新型微流体分离装置的合理设计提供基础，该装置超越宏观方法的小型化，并充分利用小尺度上的主导物理现象，例如布朗运动和胶体表面相互作用。为了利用这些复杂的现象，我们将利用当前制造技术提供的卓越控制来确定平面微流体装置的几何结构和表面化学。该策略是通过诱导单个物种的空间分区和/或控制非线性流体动力学效应，和/或通过创建选择性表面-颗粒相互作用和/或通过引导其布朗运动来创建特定的周期性模式，该模式决定悬浮颗粒的行为。在这个项目中，我们研究了颗粒系统中传输现象领域的一个具有挑战性的问题。也就是说，了解具有各向异性和异质特性的周期系统中悬浮胶体的确定性和随机行为。对这一领域的贡献可能会影响广泛的学科，从更好地理解地下水库中污染物的胶体增强传输，到体积平均技术等传统分析方法的进步。研究结果还将影响芯片设备实验室不断发展的领域，通过提供操纵悬浮物质的新方法，有望彻底改变化学科学。该项目将把研究和教育与微流体设备中粒子传输的基于网络的虚拟实验的开发结合起来。这些实验室将让用户对最先进的工程发展有一个令人兴奋的了解。同时，实验室将提供一个平台来理解运输现象的关键概念。研究与教育一体化的第二个方面是简单实验的设计，这些实验展示了在宏观尺度上控制微流体系统中传输的基本现象。具体来说，我们正在开发钢球在由乐高积木制成的平面、透明、周期性多孔介质中沉积的实验。