I-Corps: Self-Adaptive, Ultra-Low Modulus Alloys and Devices

这项拟议的活动调查了用于生物医学植入物和其他技术应用的自适应、超低模数合金的商业潜力。这项拟议的技术解决了人体骨骼与传统医用植入物中使用的合金之间的弹性模数不匹配导致的并发症，这些并发症导致骨质量损失，植入物可能松动，以及骨对意外骨折的抵抗力降低。考虑到每年骨科植入物数量的显著增加，以及由于预期寿命的持续延长和接受植入物的患者年龄的不断下降而需要更长的寿命，拟议的技术提供的植入物寿命和可靠性的改善有可能显著降低因事故而致残的伤害的可能性以及翻修手术的频率和必要性。

The proposed activity investigates the commercial potential of self-adaptive, ultra-low modulus alloys for biomedical implants and other technological applications. The proposed technology offers a solution to complications caused by the mismatch in elastic modulus between human bone and alloys used in conventional medical implants that lead to the loss of bone quality, possible loosening of the implant, and the reduced resistance of the bone to fracture from accidents.The proposed technology offers unprecedented advantages for orthopedic and dental implants. Considering the notable increase in the number of orthopedic implants every year and the need for longer lifetime implants due to continued increase in life expectancy and ever-decreasing age of patients receiving implants, the improvement in implant lifetime and reliability offered by the proposed technology has potential to significantly reduce both the probability of disabling injuries from accidents and the frequency and necessity for revision surgeries.