Controlled Evaluation of Nanoparticle Dissolution Using Atomic Force Microscopy

使用原子力显微镜控制纳米颗粒溶解评估

• 批准号: 1411385
• 负责人: Peter Vikesland
• 金额: $ 39万
• 依托单位: Virginia Polytechnic Institute and State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-01 至 2018-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1411385&HistoricalAwards=false
• 关键词: Controlled; Evaluation; Nanoparticle; Dissolution; Using

In this project, funded by the Environmental Chemical Sciences program of the NSF Chemistry Division, Professor Peter Vikesland of Virginia Tech is examining the role of particle properties on the dissolution kinetics of metallic nanoparticles. Metal nanoparticles are being developed for incorporation in a wide variety of consumer and industrial products, yet many questions remain about their longevity in diverse environments. Results from this integrated research and education effort will be disseminated in scientific publications and via presentations at relevant conferences. In addition, the results will inform outreach activities organized by Professor Vikesland, the Virginia Tech Sustainable Nanotechnology (VTSuN) Program, and the NSF-EPA Center for the Environmental Implications of Nanotechnology (CEINT). Professor Vikesland, VTSuN, and CEINT will engage K-12 and other members of the general population using hands-on activities and inform these audiences about the societal implications (both positive and negative) of nanotechnology. Professor Vikesland will utilize a highly sensitive atomic force microscope to examine how surface coatings, nanoparticle size, and metal identity affect metal nanoparticle dissolution rates. Arrays of surface adhered nanoparticles of variable consistency will be produced via nanosphere lithography and their dissolution will be probed over time. This approach enables investigation of dissolution kinetics in the absence of aggregation using realistic nanoparticle concentrations - severe limitations of many alternative methodologies. Findings from this study will aid efforts to engineer environmentally benign nanomaterials and to predict their environmental impacts.

在这项由美国国家科学基金会化学部环境化学科学项目资助的项目中，弗吉尼亚理工大学的彼得·维克斯兰教授正在研究颗粒特性对金属纳米颗粒溶解动力学的影响。金属纳米粒子正在被开发用于各种消费和工业产品中，然而，关于它们在不同环境中的寿命仍然存在许多问题。这一综合研究和教育工作的成果将在科学出版物中传播，并通过在相关会议上的介绍加以传播。此外，结果还将为维克斯兰教授、弗吉尼亚理工大学可持续纳米技术(VTSuN)计划和NSF-EPA纳米技术环境影响中心(CEINT)组织的外联活动提供信息。Vikeland教授、VTSuN和CEINT将通过实践活动让K-12和其他普通民众参与进来，并向这些受众介绍纳米技术的社会影响(包括积极和消极的影响)。维克斯兰教授将利用高灵敏度的原子力显微镜来研究表面涂层、纳米颗粒大小和金属特性如何影响金属纳米颗粒的溶解速度。通过纳米球光刻将产生不同浓度的表面附着的纳米颗粒阵列，并将随着时间的推移探测它们的溶解情况。这种方法能够在没有聚集的情况下使用现实的纳米颗粒浓度来研究溶出动力学--这是许多替代方法的严重限制。这项研究的发现将有助于设计环境友好的纳米材料并预测其对环境的影响。