GOALI: Single droplet level understanding of phase inversion emulsification to enable continuous processing

GOALI：单液滴水平了解转相乳化以实现连续加工

• 批准号: 1604536
• 负责人: Daeyeon Lee
• 金额: $ 33.82万
• 依托单位: University of Pennsylvania
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1604536&HistoricalAwards=false
• 关键词: GOALI; Single; droplet; level; understanding

CBET - 1604536PI: Lee, DaeyeonEmulsions are composed of liquid drops that are suspended in an immiscible liquid, such as oil drops in water. The drops are the dispersed phase, and the immiscible liquid is the continuous phase. Emulsions are used in the manufacture of many products, including foodstuffs, nutrients, drugs, and pesticides. Phase inversion emulsification (PIE) is a process for generating a new emulsion by inverting the phases of an existing emulsion. PIE is especially useful when it is difficult to generate the desired emulsion by other methods. For example, Xerox uses PIE to manufacture latex particles, which are used to produce toners for printing and photocopying. This GOALI project, which is a collaborative effort between the University of Pennsylvania and Xerox, will explore a variation on PIE called flow-induced PIE. In flow-induced PIE, phase inversion takes place by flowing an existing emulsion through microchannels that contain abrupt variations in their cross-sections, such as constrictions or expansions. Under proper conditions, an emulsion of oil drops in water flowing through the channel is inverted into an emulsion of water drops in oil. Experiments will be designed to explore effects of channel geometry, flow rates, wettability of the channel surface, and composition of the liquid phases on the phase inversion process. The flow-induced PIE process will allow products to be manufactured in a continuous process with reduced energy consumption, higher efficiency, and reduced environmental impact. The project will provide opportunities for students at various academic levels to participate in research. Students from underrepresented groups will be encouraged to participate through several programs at Penn, including the Louis Stokes Alliance for Minority Participation.A series of experiments will be conducted to determine effects of initial emulsion morphology and chemistry as well as channel geometry on the mechanism and efficiency of flow-induced PIE. The effect of surface wettability of the channels on the phase inversion process will be determined. Hydrodynamic parameters such as shear and extensional deformation in the microchannels will also be examined. The use of a microfluidic platform will enable the formation of model emulsions with controlled properties and the direct observation of PIE during flow. Emulsion droplets with precisely controlled size, size distribution and interfacial chemistry will be used to understand effects of emulsion morphology and chemistry on flow-induced PIE. Alternative arrangements that can promote flow-induced PIE will also be explored, including flow through a microfluidic device containing pillar arrays, which serves as a model porous medium.

CBET -1604536 PI：Lee，Daeyeon乳液由悬浮在不混溶液体中的液滴组成，例如水中的油滴。液滴是分散相，并且不混溶的液体是连续相。乳液用于许多产品的制造，包括食品、营养素、药物和杀虫剂。相转化乳化（PIE）是通过转化现有乳液的相来产生新乳液的方法。 当难以通过其他方法产生所需乳液时，PIE特别有用。例如，Xerox使用PIE制造乳胶颗粒，用于生产打印和复印用墨粉。 这个GOALI项目是宾夕法尼亚大学和施乐公司的合作项目，将探索PIE的一种变体，称为流动诱导PIE。 在流动诱导PIE中，通过使现有乳液流过在其横截面中包含突变（例如收缩或膨胀）的微通道来发生相转化。在适当的条件下，油滴在流过通道的水中的乳液被转化成水滴在油中的乳液。 实验将被设计来探索通道的几何形状，流速，通道表面的润湿性，和相转化过程中的液相的组成的影响。流动诱导PIE工艺将允许在连续工艺中制造产品，降低能耗，提高效率，并减少对环境的影响。 该项目将为不同学术水平的学生提供参与研究的机会。宾夕法尼亚大学将鼓励来自代表性不足群体的学生通过宾夕法尼亚大学的多个项目参与，包括路易斯·斯托克斯少数族裔参与联盟。将进行一系列实验来确定初始乳液形态和化学以及通道几何形状对流动诱导PIE的机制和效率的影响。 将确定通道的表面润湿性对相转化过程的影响。 流体动力学参数，如剪切和拉伸变形的微通道也将被检查。 微流体平台的使用将使得能够形成具有受控性质的模型乳液，并在流动期间直接观察PIE。具有精确控制的尺寸、尺寸分布和界面化学的乳液液滴将用于了解乳液形态和化学对流动诱导PIE的影响。还将探索可以促进流动诱导的PIE的替代布置，包括流过包含柱阵列的微流体装置，其用作模型多孔介质。