Orally active spider toxins: a novel paradigm for control of insect pests

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Many insects and other arthropods are serious pests of Australian crops, livestock, and pets. Australian farmers spend about $300 million per annum on insecticides and acaricides, while Australian consumers spend more than $100 million annually on insecticides for use around the home and garden, and on pets. Viruses disseminated by arthropods are also responsible for diseases such as dengue, Japanese encephalitis, and Ross River fever. Unfortunately, many of these arthropod pests have developed resistance to chemical insecticides. This aim of this research program is to develop a new generation of environmentally-friendly natural products that can be used to control arthropod pests on pets, farms, and around the home and garden.