Nanomechanical Switches for ON-OFF Catalysis and Interswitch Communication

用于开关催化和开关间通信的纳米机械开关

• 批准号: 237115133
• 负责人: Professor Dr. Michael Schmittel
• 金额: --
• 依托单位: Arbeitsgruppe Organische Chemie I
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2013
• 资助国家: 德国
• 起止时间: 2012-12-31 至 2019-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/237115133?language=en
• 关键词: Nanomechanical; Switches; OFF; Catalysis; Interswitch

Coupled molecular switching plays an important role in almost all aspects of our existence. For instance, biological switches intercommunicate chemically to regulate in detail all processes that are elementary for life. Although, molecular switches, for example sliding switches (= shuttles) on the basis of rotaxanes/catenanes, have celebrated startling success, establishing a directed chemical communication among them is a terra incognita. As an alternative we intend, based on latest developments from our research, to further develop the family of triangular nanoswitches that operate via chemical input and output signals. The focus will be on signaling in catalytically active systems and on enabling a variety of regulatory scenarios: from communication and catalysis to catalytic reaction networks administrated by two nanoswitches and to feedback control in catalysis. This work should thus not only improve our understanding of chemical communication on the nanoscale, but it may equally open new vistas for systems chemistry; for example, how can one interconnect molecule-based gates and storage units as well as artificial synapses via chemical exchange processes.

偶联分子开关几乎在我们生活的各个方面起着重要的作用。例如，生物开关通过化学方式相互交流，详细地调节生命的所有基本过程。虽然分子开关，例如基于轮烷/链状烷的滑动开关（=梭子），已经取得了惊人的成功，但在它们之间建立定向化学通信仍然是一个未知领域。作为一种替代方案，我们打算根据我们研究的最新进展，进一步开发通过化学输入和输出信号操作的三角形纳米开关家族。重点将放在催化活性系统中的信号转导和各种调节场景的实现上：从通信和催化到由两个纳米开关管理的催化反应网络，以及催化中的反馈控制。因此，这项工作不仅应该提高我们对纳米尺度上化学通讯的理解，而且可能同样为系统化学开辟新的前景；例如，如何通过化学交换过程将基于分子的门和存储单元以及人工突触连接起来。

项目成果

Catch-Release System for Dosing and Recycling Silver(I) Catalyst with Status of Catalytic Activity Reported by Fluorescence.

• DOI: 10.1021/jacs.9b01182
• 发表时间: 2019-03
• 期刊: Journal of the American Chemical Society
• 影响因子: 15
• 作者: Indrajit Paul;Nikita Mittal;Soumen De;M. Bolte;M. Schmittel