MRI: Acquisition of a Flow Cytometer/Sorter (FCMS) at Lamar University

MRI：在拉马尔大学购买流式细胞仪/分选仪 (FCMS)

• 批准号: 1919295
• 负责人: James Henry
• 金额: $ 32.2万
• 依托单位: Lamar University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-15 至 2021-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1919295&HistoricalAwards=false
• 关键词: MRI; Acquisition; Flow; Cytometer; Sorter

The acquisition of a flow cytometer/cell sorter will enable a multi-disciplinary group of researchers and students at Lamar University to perform analyses that involve quantitative single cell biological analysis and sorting. The instrument will facilitate research associated with Alzheimer's disease therapeutic screening and identification, high throughput drug screening, identification of unique cancer types and markers, and analysis of environmental toxins. The availability of this equipment will increase interdisciplinary and interdepartmental collaborative research opportunities within Lamar University as well as with other organizations, and it will enrich the training of graduate and undergraduate students. Graduate and undergraduate students in microbiology, biochemistry, chemical engineering, and civil and environmental engineering classes will have access to this instrument, thereby strengthening curriculum content at the undergraduate and graduate levels.Flow cytometry/cell sorting is a technique for doing high level qualitative and quantitative analysis on a per cell basis for large cell populations in a high-throughput manner. The acquisition of a flow cytometer/cell sorter will generate the capability to perform high population count, quantitative single cell biological analysis and sorting. The availability of this instrument, therefore, will facilitate research related to drug discovery, biofuels, environmental impact, aging, and cancer characterization. Such work will lead to significantly improved research related to in vitro studies, including high throughput drug screening, the identification of unique cancer types and markers, and the determination of environmental toxins.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

流式细胞仪/细胞分选仪的收购将使拉马尔大学的多学科研究人员和学生小组能够进行涉及定量单细胞生物分析和分选的分析。 该仪器将促进与阿尔茨海默病治疗筛选和鉴定、高通量药物筛选、独特癌症类型和标志物鉴定以及环境毒素分析相关的研究。 该设备的可用性将增加拉马尔大学内以及与其他组织的跨学科和跨部门合作研究机会，并将丰富研究生和本科生的培训。 微生物学、生物化学、化学工程、土木与环境工程专业的研究生和本科生将有机会使用该仪器，从而加强本科和研究生阶段的课程内容。流式细胞术/细胞分选是一种以高通量方式对大细胞群进行高水平定性和定量分析的技术。 流式细胞仪/细胞分选仪的获得将产生执行高群体计数、定量单细胞生物学分析和分选的能力。因此，该仪器的可用性将促进与药物发现、生物燃料、环境影响、衰老和癌症表征相关的研究。 这些工作将导致显着改善研究相关的体外研究，包括高通量药物筛选，确定独特的癌症类型和标志物，并确定环境toxics.This奖项反映了NSF的法定使命，并已被认为是值得通过评估使用基金会的智力价值和更广泛的影响审查标准的支持。