MRI: Acquisition of a 400 MHz Nuclear Magnetic Resonance (NMR) Spectrometer at Miami University

MRI:在迈阿密大学购买 400 MHz 核磁共振 (NMR) 波谱仪

基本信息

  • 批准号:
    1919850
  • 负责人:
  • 金额:
    $ 29.58万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
    Standard Grant
  • 财政年份:
    2019
  • 资助国家:
    美国
  • 起止时间:
    2019-09-01 至 2022-08-31
  • 项目状态:
    已结题

项目摘要

This award is supported by the Major Research Instrumentation and the Chemistry Instrumentation Programs. Professor Christopher Hartley from Miami University in Ohio and colleagues Michael Crowder, Meredith Erb, Dominik Konkolewicz and Wei Liu are acquiring a 400 MHz nuclear magnetic resonance (NMR) spectrometer equipped with flow monitoring accessory to monitor kinetics and an automatic sampler. This spectrometer allows research in a variety of fields such as those that accelerate chemical reactions of significant economic importance, as well as facilitating studies of biologically relevant species. In general, Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful tools available to chemists for the elucidation of the structure of molecules. It is used to identify unknown substances, to characterize specific arrangements of atoms within molecules, and to study the dynamics of interactions between molecules in solution or in the solid state. Access to state-of-the-art NMR spectrometers is essential to chemists who are carrying out frontier research. The NMR studies improve understanding of synthetic organic/inorganic chemistry, materials chemistry and biochemistry. This instrument is an integral part of teaching as well as research. This broadly accessible instrumentation strengthens the regional NMR analytical infrastructure and help advance the scientific careers of many regular users of undergraduate and graduate researchers and postdocs. The spectrometer enriches the education and training experience of underrepresented undergraduate students in several NSF supported science, technology, engineering and mathematics (STEM) programs and several hundred undergraduate students in chemistry and biochemistry laboratory classes at this institution.The award is aimed at enhancing research and education at all levels. The spectrometer is especially useful for studying o-phenylene foldamers and non-equilibrium systems and for monitoring flurorination reactions. It is also essential or studying kinetics of polymerization and small-molecule reactions and metallo-beta-lactamase enzymes. The spectrometer aids researchers exploring coordination compounds of high-spin cobalt(II) and those studying enantioselective catalysis. It is also in exploration of heterogeneous electrocatalysis of carbon dioxide and methane.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.
该奖项由主要研究仪器和化学仪器计划支持。来自俄亥俄州迈阿密大学的Christopher Hartley教授及其同事Michael Crowder、Meredith Erb、Dominik Konkolewicz和Wei Liu正在购买一台400 MHz核磁共振(NMR)光谱仪,该光谱仪配备有流量监测附件以监测动力学和自动采样器。该光谱仪可用于各种领域的研究,例如加速具有重要经济意义的化学反应,以及促进生物相关物种的研究。一般来说,核磁共振(NMR)光谱是化学家用来阐明分子结构的最有力的工具之一。它用于识别未知物质,表征分子内原子的特定排列,并研究溶液或固态分子之间相互作用的动力学。对于从事前沿研究的化学家来说,使用最先进的NMR光谱仪是必不可少的。NMR研究提高了对合成有机/无机化学,材料化学和生物化学的理解。该仪器是教学和研究的重要组成部分。这种广泛使用的仪器加强了区域NMR分析基础设施,并有助于推动许多本科生和研究生研究人员和博士后的常规用户的科学事业。光谱仪丰富了教育和培训经验的代表性不足的本科生在几个国家科学基金会支持的科学,技术,工程和数学(STEM)计划和数百名本科生在化学和生物化学实验室类在这个机构。该奖项旨在加强各级研究和教育。该光谱仪特别适用于研究邻苯撑折叠体和非平衡体系以及监测氟化反应。它也是必不可少的或研究聚合和小分子反应和金属β-内酰胺酶的动力学。光谱仪帮助研究人员探索高自旋钴(II)的配位化合物和那些研究对映选择性催化的人。该奖项反映了NSF的法定使命,并通过使用基金会的知识价值和更广泛的影响审查标准进行评估,被认为值得支持。

项目成果

期刊论文数量(21)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Photons and Photocatalysts as limiting reagents for PET-RAFT photopolymerization
  • DOI:
    10.1016/j.cej.2022.141007
  • 发表时间:
    2022-12
  • 期刊:
  • 影响因子:
    15.1
  • 作者:
    B. Parnitzke;Tochukwu Nwoko;Kate G. E. Bradford;Nethmi De Alwis Watuthanthrige;Kevin Yehl;C. Boyer
  • 通讯作者:
    B. Parnitzke;Tochukwu Nwoko;Kate G. E. Bradford;Nethmi De Alwis Watuthanthrige;Kevin Yehl;C. Boyer
Network polymers incorporating lipid-bilayer disrupting polymers: towards antiviral functionality
结合脂质双层破坏聚合物的网络聚合物:实现抗病毒功能
  • DOI:
    10.1039/d2py00602b
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    4.6
  • 作者:
    Burridge, Kevin M.;Rahman, Monica S.;De Alwis Watuthanthrige, Nethmi;Gordon, Emma;Shah, Muhammad Zeeshan;Chandrarathne, Bhagya Madhushani;Lorigan, Gary A.;Page, Richard C.;Konkolewicz, Dominik
  • 通讯作者:
    Konkolewicz, Dominik
Interpenetrated triple network polymers: synergies of three different dynamic bonds
互穿三网络聚合物:三种不同动态键的协同作用
  • DOI:
    10.1039/d2py00575a
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    4.6
  • 作者:
    Wanasinghe, Shiwanka V.;De Alwis Watuthanthrige, Nethmi;Konkolewicz, Dominik
  • 通讯作者:
    Konkolewicz, Dominik
A general model for the ideal chain length distributions of polymers made with reversible deactivation
  • DOI:
    10.1039/d1py01331a
  • 发表时间:
    2022-01-07
  • 期刊:
  • 影响因子:
    4.6
  • 作者:
    Kearns, Madison M.;Morley, Colleen N.;Konkolewicz, Dominik
  • 通讯作者:
    Konkolewicz, Dominik
Aromatic foldamers as molecular springs in network polymers
芳香族折叠分子作为网络聚合物中的分子弹簧
  • DOI:
    10.1039/d2cc01223e
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    4.9
  • 作者:
    Miller, K. Andrew;Dodo, Obed J.;Devkota, Govinda Prasad;Kirinda, Viraj C.;Bradford, Kate G.;Sparks, Jessica L.;Hartley, C. Scott;Konkolewicz, Dominik
  • 通讯作者:
    Konkolewicz, Dominik
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Christopher Hartley其他文献

ENDOSCOPIC ULTRASOUND-GUIDED FINE NEEDLE BIOPSY OF THE PANCREAS AND DIRECT ORAL ANTICOAGULANTS: RANDOMIZED CONTROLLED PRECLINICAL TRIAL
  • DOI:
    10.1016/j.gie.2022.04.1255
  • 发表时间:
    2022-06-01
  • 期刊:
  • 影响因子:
    7.500
  • 作者:
    Ana Garcia Garcia de Paredes;Ariosto H. Hernandez-Lara;Christopher Hartley;Rajiv K. Pruthi;Rondell Graham;Jad P. AbiMansour;Eric J. Vargas;Andrew C. Storm;Ferga C. Gleeson;Michael J. Levy;Elizabeth Rajan
  • 通讯作者:
    Elizabeth Rajan
1452 Steatosis Evaluation in the Digital Age: What Can Machines Tell Us About Our Methods?
数字时代的脂肪变性评估:机器能告诉我们关于我们方法的什么?
  • DOI:
    10.1016/j.labinv.2024.103691
  • 发表时间:
    2025-03-01
  • 期刊:
  • 影响因子:
    4.200
  • 作者:
    Saadiya Nazli;Abdelrahman Shabaan;Bashar Hasan;Byoung Uk Park;Rofyda Elhalaby;Priyadharshini Sivasubramaniam;Adilson DaCosta;Lindsey Smith;Rondell Graham;Christopher Hartley;Daniela Allende;Murli Krishna;Marcela Salomao;Rish Pai;Kristina Matkowskyj;Hee Eun Lee;Stephen Lagana;Zongming (Eric) Chen;Jason Lewis;Andrew Cannon;Roger Moreira
  • 通讯作者:
    Roger Moreira
Sa2054 QUANTITATIVE ASSESSMENT OF DUPILUMAB TREATMENT IN PEDIATRIC PATIENTS CHARACTERIZED BY AN ARTICFICAL INTELLIGENCE ANALYSIS OF HISTOPATHOLOGIC FEATURES OF EOSINOPHILIC ESOPHAGITIS
  • DOI:
    10.1016/s0016-5085(24)01888-2
  • 发表时间:
    2024-05-18
  • 期刊:
  • 影响因子:
  • 作者:
    Puanani Hopson;Andrew Cannon;Roland Tian;Luisa Ricaurte Archila;Priyadharshini Sivasubramaniam;Ameya Patil;Christopher Hartley;Imad Absah;Roger K. Moreira
  • 通讯作者:
    Roger K. Moreira
Accuracy of Preliminary Pathology for Robotic Bronchoscopic Biopsy
  • DOI:
    10.1016/j.athoracsur.2022.11.022
  • 发表时间:
    2023-11-01
  • 期刊:
  • 影响因子:
  • 作者:
    Linh H. Vu;Alejandra Yu Lee-Mateus;Eric S. Edell;Christopher Hartley;Robert A. Vierkant;Sebastian Fernandez-Bussy;Janani Reisenauer
  • 通讯作者:
    Janani Reisenauer
ASSESSMENT OF A NOVEL ARTIFICIAL INTELLIGENCE-ENHANCED APPLICATION DESIGNED TO ASSIST THE CYTOLOGIC EVALUATION OF BILIARY STRICTURES: RESULTS OF A DOUBLE-BLINDED, PRAGMATIC TRIAL
评估一种旨在辅助胆道狭窄细胞学评估的新型人工智能增强应用程序:一项双盲、实用试验的结果
  • DOI:
    10.1016/j.gie.2023.04.1937
  • 发表时间:
    2023-06-01
  • 期刊:
  • 影响因子:
    7.500
  • 作者:
    Neil Marya;Christopher Hartley;Patrick Powers;Melanie Bois;Sarah Kerr;Judith Jebastin Thangaiah;Mary Kittle Francis;Marie Passow;Daniel Norton;Ferga Gleeson;Barham Abu Dayyeh;Aliana Bofill-Garcia;Vinay Chandrasekhara;Gregory Gores;Benjamin Kipp;Ryan Law;John Martin;Bret Petersen;Lewis Roberts;Andrew Storm;Michael Levy
  • 通讯作者:
    Michael Levy

Christopher Hartley的其他文献

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{{ truncateString('Christopher Hartley', 18)}}的其他基金

Short- and Long-Range Structural Complexity from Ortho-arylene Foldamers
邻亚芳基折叠体的短程和长程结构复杂性
  • 批准号:
    2304670
  • 财政年份:
    2023
  • 资助金额:
    $ 29.58万
  • 项目类别:
    Standard Grant
Dynamic control and self-assembly of ortho-phenylene foldamers
邻亚苯基折叠体的动态控制与自组装
  • 批准号:
    1904236
  • 财政年份:
    2019
  • 资助金额:
    $ 29.58万
  • 项目类别:
    Standard Grant
ortho-Phenylenes in Complex Foldamer Architectures
复杂Foldamer架构中的邻亚苯基
  • 批准号:
    1608213
  • 财政年份:
    2016
  • 资助金额:
    $ 29.58万
  • 项目类别:
    Standard Grant
o-Phenylenes: Controlled Folding and Directed Oxidative Planarization
邻亚苯基:受控折叠和定向氧化平坦化
  • 批准号:
    1306437
  • 财政年份:
    2013
  • 资助金额:
    $ 29.58万
  • 项目类别:
    Standard Grant
ortho-Phenylene Oligomers and Graphene Nanoribbons
邻亚苯基低聚物和石墨烯纳米带
  • 批准号:
    0910477
  • 财政年份:
    2009
  • 资助金额:
    $ 29.58万
  • 项目类别:
    Standard Grant

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