Liquid Chromatography Tandem Mass Spectrometry Steroid Analysis Facility

液相色谱串联质谱类固醇分析设备

• 批准号: LE0883078
• 负责人: Prof David Handelsman
• 金额: $ 23.74万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-02-21 至 2008-10-28
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE0883078
• 关键词: Liquid; Chromatography; Tandem; Mass; Spectrometry

This first of a new generation of ultra-sensitive analytical mass spectrometers for small molecules will be established as a national assay facility allowing all Australian researchers open access to a new dimension of highly accurate and simultaneous measurements of multiple bodily chemicals such as steroids, vitamins and hormones. It is crucial to developing new knowledge in basic, developmental and pathological cell biology and for underpinning commercial developments of new molecular targets for therapeutic drugs for many diseases including cancer, cardiovascular disease and reproductive disorders. This facility is pivotal to maintaining international competitiveness in many areas of biological research in national priority areas.

这是新一代超灵敏小分子分析质谱仪中的第一台，将作为一个国家检测设施，允许所有澳大利亚研究人员开放获得高度准确和同时测量多种身体化学物质的新维度，如类固醇，维生素和激素。它对于发展基础、发育和病理细胞生物学方面的新知识，对于支持包括癌症、心血管疾病和生殖系统疾病在内的许多疾病治疗药物的新分子靶点的商业开发至关重要。这一设施对于在国家优先领域的许多生物研究领域保持国际竞争力至关重要。