Advanced technologies for integrated micro systems

微器件和芯片实验室技术中的合成化学是技术要求很高的研究领域，需要广泛的技术发展才能融合。因此，项目8的目的是在微流体中集成分析和合成系统的技术方面开展工作，并为整个研究单位提供研究结果和相应的使能技术。具体而言，该项目旨在将液滴微流体和芯片色谱联用，以实现单个液滴化学成分的阅读。 此外，还将研究一种制造微流体设备的新方法，使所有项目合作伙伴能够快速获得定制的高质量微流体设备。为此，将探索和进一步开发选择性激光蚀刻技术，以获得由玻璃、石英和蓝宝石制成的微流控芯片。此外，将开发方法来为这些结构配备金属电极。在研究单位的背景下，重要的应用是芯片集成的生物阻抗谱和芯片接口与电喷雾质谱，以及与离子迁移谱。 通过这种方式，项目8成为研究单位项目之间的技术桥梁，提供必要的技术专长，并促进综合微型实验室的最新技术水平。

Synthetic chemistry in microdevices and lab on chip technology are technically demanding research fields requiring extensive technical development for their fusion. Therefore, the aim of project 8 is to work on the technical aspects of integrating analysis and synthesis systems in microfluidics and provide the findings and respective enabling technology to the whole research unit. Specifically, the project aims to hyphenate droplet microfluidics and on-chip chromatography to enable the reading of the chemical contents of single droplets. Furthermore, a novel approach for manufacturing microfluidic devices will be investigated to give all project partners rapid access to tailor-made high quality microfluidic devices. For this purpose, the technology of selective laser etching will be explored and further developed to give access to microfluidic chips made from glass, quartz and sapphire. Furthermore approaches will be developed to equip these structures with metal electrodes. Important application in the context of the research unit are chip-integrated bioimpedance spectroscopy and chip interfacing with electrospray mass spectrometry, as well as with ion mobility spectrometry. In this way, project 8 serves as a technology bridge between the research unit’s projects providing essential technical expertise and furthering the state of the art in integrated micro laboratories.