Advanced technologies for integrated micro systems

微器件中的合成化学和芯片实验室技术是技术要求很高的研究领域，需要广泛的技术开发来实现它们的融合。因此，项目8的目的是致力于在微流体中整合分析和合成系统的技术方面的工作，并向整个研究单位提供研究结果和各自的使能技术。具体地说，该项目的目标是联用液滴微流体和芯片上的层析，以便能够读取单个液滴的化学含量。此外，将研究一种制造微流控设备的新方法，使所有项目合作伙伴能够快速获得定制的高质量微流控设备。为此，将探索和进一步发展选择性激光刻蚀技术，以获得由玻璃、石英和蓝宝石制成的微流控芯片。此外，还将开发为这些结构配备金属电极的方法。在研究单位中的重要应用是芯片集成生物阻抗谱和芯片与电喷雾质谱仪的接口，以及与离子迁移率光谱的接口。通过这种方式，项目8在研究单位的项目之间起到了技术桥梁的作用，提供了必要的技术专业知识，并促进了综合微型实验室的最先进水平。

Synthetic chemistry in microdevices and lab on chip technology are technically demanding research fields requiring extensive technical development for their fusion. Therefore, the aim of project 8 is to work on the technical aspects of integrating analysis and synthesis systems in microfluidics and provide the findings and respective enabling technology to the whole research unit. Specifically, the project aims to hyphenate droplet microfluidics and on-chip chromatography to enable the reading of the chemical contents of single droplets. Furthermore, a novel approach for manufacturing microfluidic devices will be investigated to give all project partners rapid access to tailor-made high quality microfluidic devices. For this purpose, the technology of selective laser etching will be explored and further developed to give access to microfluidic chips made from glass, quartz and sapphire. Furthermore approaches will be developed to equip these structures with metal electrodes. Important application in the context of the research unit are chip-integrated bioimpedance spectroscopy and chip interfacing with electrospray mass spectrometry, as well as with ion mobility spectrometry. In this way, project 8 serves as a technology bridge between the research unit’s projects providing essential technical expertise and furthering the state of the art in integrated micro laboratories.