CX3C chemokine signalling in the olfactory epithelium and its role in the self regeneration of the olfactory system

嗅觉上皮中CX3C趋化因子信号传导及其在嗅觉系统自我再生中的作用

• 批准号: DP0774113
• 负责人: Prof Dr Marc Ruitenberg
• 金额: $ 19.81万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2007
• 资助国家: 澳大利亚
• 起止时间: 2007-01-01 至 2010-03-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0774113
• 关键词: CX3C; chemokine; signalling; olfactory; epithelium

The current proposal will explore new venues in adult neural stem cell research and contribute to the further development of molecular biology and neuroscience research in Western Australia and Australia. The use of neural stem cells holds therapeutic promise for the treatment of a wide variety of neurological conditions, including neurotrauma and stroke. The proposed research will provide new data on the fundamental cellular and molecular events that are required to trigger the birth, differentiation and conditions for growth of new neurons in the adult nervous system. The generation of such insights will be critical for any translational research.

目前的提案将探索成人神经干细胞研究的新途径，并有助于西澳大利亚州和澳大利亚分子生物学和神经科学研究的进一步发展。神经干细胞的使用为治疗包括神经创伤和中风在内的各种神经系统疾病提供了治疗前景。拟议的研究将提供有关基本细胞和分子事件的新数据，这些事件是触发成人神经系统中新神经元的出生，分化和生长条件所必需的。这种见解的产生对任何翻译研究都至关重要。