Continuous size- and shape-selective separation of nanoparticles

纳米颗粒的连续尺寸和形状选择性分离

• 批准号: 382080299
• 负责人: Professor Dr.-Ing. Wolfgang Peukert
• 金额: --
• 依托单位: Lehrstuhl für Feststoff- und Grenzflächenverfahrenstechnik (LFG)
• 依托单位国家: 德国
• 项目类别: Priority Programmes
• 财政年份: 2017
• 资助国家: 德国
• 起止时间: 2016-12-31 至 2021-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/382080299?language=en
• 关键词: Continuous; size; shape; selective; separation

Scale-up of syntheses for anisotropic nanoparticles usually results in rather broad aspect ratio distributions and spherical particles as side-products. Thus, a size and shape selective classification step is required to tune the product properties according to the needs of the application. The establishment of technical relevant processes for size and shape selective classification of spherical and anisotropic nanoparticles is challenging and requires multidimensional particle characterization. Analytical ultracentrifugation is used as central analytical method as it is the most accurate method for in-suspension analytics of nanoparticles in a broad size range and provides information regarding shape anisotropy. Additionally, standard methods of particle characterization will be used to study possibilities for the reconstruction of two-dimensional distributions.A key objective of this project is separation of anisotropic nanoparticles (rods and platelets) from spheres and classification regarding aspect ratio using antisolvent precipitation. Moreover, the separation process will be described quantitatively by analytical methods for multidimensional particle characterization. As the size and shape dependent particle interactions govern the result of antisolvent precipitation these interactions are studied in detail experimentally and by extended DLVO models. Additionally the potential of an electrophoretic classification is explored by measuring the electrophoretic mobility as a function of nanoparticle size, shape and aspect ratio.The investigations will be done exemplary for SiO2 platelets and ZnO and Au rods.

各向异性纳米颗粒合成的规模扩大通常导致相当宽的纵横比分布和球形颗粒作为副产物。因此，需要尺寸和形状选择性分类步骤以根据应用的需要调整产品性质。球形和各向异性纳米颗粒的尺寸和形状选择性分类的技术相关过程的建立是具有挑战性的，并且需要多维颗粒表征。分析超离心用作中心分析方法，因为它是用于宽尺寸范围内纳米颗粒的悬浮液分析的最准确方法，并提供关于形状各向异性的信息。 此外，标准的颗粒表征方法将被用来研究重建二维分布的可能性。本项目的一个关键目标是从球体中分离各向异性的纳米颗粒（棒和片），并使用反溶剂沉淀法对纵横比进行分类。此外，分离过程将通过多维颗粒表征的分析方法定量描述。由于大小和形状依赖的颗粒相互作用的反溶剂沉淀的结果，这些相互作用进行了详细的实验研究和扩展的DLVO模型。此外，通过测量电泳迁移率作为纳米颗粒的大小，形状和纵横比的函数，探讨了电泳分类的潜力。调查将做示范性的二氧化硅血小板和ZnO和Au棒。