Research of Microactuators Applied to Intravascular Microvehicles

该项目旨在开发血管内使用的微型机械及其设计和制造技术。该项目是医用微机械制造的第一次尝试，也是建立医学工程研究的第一个微机械中心。该项目于1988年9月开工，建成了硅工艺和光刻技术应用的微机械制造系统。在该系统中，可以使用直径为2英寸的硅片，并开发了肌节状集成微驱动器。为了在三维空间中加工和装配微小零件，引入了微操作系统和三轴加工系统，并加工出了大量的微小零件。利用该系统研制了毫米级微型人工心脏瓣膜。为了开发血管内机器，我们应用了激光血管成形术系统，这是另一个生物医学项目开发的，带有系绳的微血管内载体已经设计和组装完成。在这些发展的轨迹下，我们发现了一种新的微执行器设计原理，并对其理论背景进行了研究。

The project was aimed at developing micromachines for intravascular use itself and their designing and fabrication technologies. The project is the first trial for producing the micromachine in medicine and also establishing the first micromachine center in the medical engineering research. The project was started on September, 1988, and built a micromachine fabrication system where silicon process and photolithography technology became applicable. In the system, a silicon wafer of 2 inch diameter can be used, and sarcomere like integrated microactuators has been developed. For machining and assembling microparts in the three dimensional space, a micromanipulation system and a three axial machining system were intoduced and many microparts were produced. A micro artificial heart valve in millimeter size has been developed with the system. For developing intravascular machines, we have applied laser angioplasty systems, which were developed another biomedical project The micro-intravascular vehicles with tethers has been designed and been assembled. Under the pathway of these development, we found a new microactualer designing principle, and its theroretical background has been studied.