Research of Microactuators Applied to Intravascular Microvehicles

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The project was aimed at developing micromachines for intravascular use itself and their designing and fabrication technologies. The project is the first trial for producing the micromachine in medicine and also establishing the first micromachine center in the medical engineering research. The project was started on September, 1988, and built a micromachine fabrication system where silicon process and photolithography technology became applicable. In the system, a silicon wafer of 2 inch diameter can be used, and sarcomere like integrated microactuators has been developed. For machining and assembling microparts in the three dimensional space, a micromanipulation system and a three axial machining system were intoduced and many microparts were produced. A micro artificial heart valve in millimeter size has been developed with the system. For developing intravascular machines, we have applied laser angioplasty systems, which were developed another biomedical project The micro-intravascular vehicles with tethers has been designed and been assembled. Under the pathway of these development, we found a new microactualer designing principle, and its theroretical background has been studied.