Investigation of color tuning mechanism in rhodopsins and production of multi-colored pigments

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Rhodopsins are known to show a large variation in their colors depending on the interaction between the apoprotein (opsin) and the retinal chromophore. In this project, we have investigated the color tuning mechanism in the rhodopsins and have also produced molecules showing a variety of colors such as blue, orange, red and purple, without loss of biological function. Thus the combination of experimental and theoretical studies could provide a useful research tool in a number of scientific fields.