Extinction of constitutive heterochromatin blocks in humans: structural analysis for clarification of mechanisms
Extinction of constitutive heterochromatin blocks in humans: structural analysis for clarification of mechanisms
批准号:
23657165
负责人:
KOGA Akihiko
金额:
$2.33万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Challenging Exploratory Research
财政年份:
2011
资助国家:
日本
项目状态:
已结题
起止时间:
2011 至 2012
中文摘要
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英文摘要
This study deals with rapid changes in the amount of constitutive heterochromatin, including emergence, amplification, reduction and extinction. These changes are frequently observed in many primate groups, such as hominids and gibbons. Cloning, sequencing and hybridization experiments revealed that such rapid changes are associated with integration of repetitive sequencesinto the centromere or telomere and the speed of change depends on their nucleotide sequences.
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Heterochromatin blocks constituting the entire short arms of acrocentric chromosomes of Azara's owl monkey: formation processes inferred from chromosomal locations(ヨザルのアクロセントリック染色体短腕を構成するヘテロクロマチン:染色体上の配置から推測される形成過程)
构成阿扎拉鸮猴近端着丝粒染色体整个短臂的异染色质块:从染色体位置推断的形成过程
DOI:
--
发表时间:
2013
期刊:
DNA Research
影响因子:
4.1
作者:
[Prakhongcheep O, Chaiprasertsri N, Terada S, Hirai Y, Srikulnath K, Hirai H, *Koga A]
通讯作者:
*Koga A
テナガザルの染色体端部にある大規模ヘテロクロマチンの主成分
长臂猿染色体末端大规模异染色质的主要成分
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[I H Susilowati, A Yasukouchi, 平井啓久・原暢・平井百合子・古賀章彦]
通讯作者:
平井啓久・原暢・平井百合子・古賀章彦
テナガザルにみられるトランスポゾンのゲノムへの影響:セントロメアへのヘテロクロマチンの供給
长臂猿中发现的转座子对基因组的影响:向着丝粒提供异染色质
DOI:
--
发表时间:
2012
期刊:
影响因子:
--
作者:
[S.Kawaguchi, O.Kambara, M.Shibata, H.Kandori, K.Tominaga, 古賀章彦(京都大・霊長研),原暢(京都大・霊長研),Israt Jahan(京都大・霊長研),平井百合子(京都大・霊長研),平井啓久(京都大・霊長研)]
通讯作者:
古賀章彦(京都大・霊長研),原暢(京都大・霊長研),Israt Jahan(京都大・霊長研),平井百合子(京都大・霊長研),平井啓久(京都大・霊長研)
京都大学霊長類研究所
京都大学灵长类研究所
DOI:
--
发表时间:
期刊:
影响因子:
--
作者:
[]
通讯作者:
DOI:
10.1038/hdy.2012.28
发表时间:
2012-09-01
期刊:
HEREDITY
影响因子:
3.8
作者:
[Koga, A., Hirai, Y., Hirai, H.]
通讯作者:
Hirai, H.
共 9 条
Rapid karyotypic changes in a primate taxon: possibility of participation of repetitive DNA as chromosome breakage inducer
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批准号:25650152
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.58万
-
财政年份:2013
-
负责人:KOGA Akihiko
-
依托单位:
Fluctuation in the size of species-specific repetitive DNA of hominoids: quantitative analysis by comparative genomics
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批准号:24370098
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.98万
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财政年份:2012
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负责人:KOGA Akihiko
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依托单位:
Factors causing sudden increase in the transposition frequency of transposable elements in medaka fish
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批准号:19570003
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.83万
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财政年份:2007
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负责人:KOGA Akihiko
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依托单位:
Transposition mechanisms and biotechnology application of the medaka fish To12 transposable element
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批准号:10216205
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$17.92万
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财政年份:1998
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负责人:KOGA Akihiko
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依托单位:
Transposition mechanism of DNA-type transposable elements of the medaka fish
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批准号:09680672
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.54万
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财政年份:1997
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负责人:KOGA Akihiko
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依托单位:
海外基金