Advanced utilization of fermented food by-products: Development of Eco-immuno feeds"supporting health and environment

在本研究中，为了更好地利用乳酸菌发酵液这一未被充分利用的资源，我们重点研究了乳酸菌发酵液及其相关产品中的免疫生物和免疫原性，并对其进行了基础分析，以开发一种新的“免疫生态饲料”，作为牲畜抗菌替代品，有助于降低健康危害风险。具体而言，评价了该液体的安全性和对猪肠细胞的免疫调节作用，并进行了体内确证研究和体外机制的详细研究。

In this study, for beneficial use of lactic acid bacterial fermentation liquid as underutilized resources, we focused on immunobiotics and immunogenics in the liquid and relating products, and examined fundamental analysis to develop as a novel “Immuno-Eco Feeds" contributing to the reduction of health hazards risk as livestock antimicrobial alternatives. Specifically, a safety of the liquid and immuneregulatory effects in porcine intestinal cells were evaluated, and in vivo confirmation study and in vitro detailed study of its mechanisms were also conducted.