Locating genes for cognitive traits using linkage and association analyses

使用连锁和关联分析定位认知特征的基因

• 批准号: DP0664638
• 负责人: Prof Nicholas Martin
• 金额: $ 35.34万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-01-01 至 2009-01-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0664638
• 关键词: Locating; genes; cognitive; traits; using

Our study is the 1st in the world to find significant linkage for IQ.The dataset is one of only 2 such in the world (based on sample size, range & type of measures).Identifying genes for cognitive ability using healthy subjects is important in understanding individual differences in normal cognitive functioning, but it may also provide clues into the underlying mechanisms of impaired cognitive ability. Diverging conditions like reading disorder, schizophrenia, depression, alcoholism, and dementia all share deficits in cognitive ability.Downstream practical applications of identifying 'genes for cognition' include better educational, behavioural and biomedical management of learning and memory disorders, and other intellectual disabilities.

我们的研究是世界上第一个发现与智商有显著联系的研究。该数据集是世界上仅有的两个这样的数据集之一（基于样本量，范围和测量类型）。使用健康受试者识别认知能力的基因对于理解正常认知功能的个体差异很重要，但它也可能为认知能力受损的潜在机制提供线索。阅读障碍、精神分裂症、抑郁症、酗酒和痴呆等不同的疾病都有认知能力缺陷。识别“认知基因”的下游实际应用包括更好的教育、行为和生物医学管理学习和记忆障碍，以及其他智力残疾。