Light-activated Bioconjugates for Applications in Synthesis and Biosensing

用于合成和生物传感应用的光激活生物共轭物

• 批准号: DP0666325
• 负责人: Prof Pall Thordarson
• 金额: $ 52.2万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-01-01 至 2011-06-30
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0666325
• 关键词: Light; activated; Bioconjugates; Applications; Synthesis

This project will allow the Australian biotechnology industry to develop better diagnostic biosensors that are controlled using light, making them cheaper and faster than the current generation of electronically controlled biosensors. Improvements in the response time of biosensors can be a matter of life and death, for instance, during a surgical operation. The project will benefit the pharmaceutical industry as it will allow the making of so-called chiral drugs cheaper and safer but problems with the purity of chiral drugs have in the past caused serious side-effects such as in the tragic case of thalidomide.

该项目将使澳大利亚生物技术行业能够开发出更好的诊断生物传感器，这些传感器使用光进行控制，使其比当前一代的电子控制生物传感器更便宜和更快。例如，在外科手术期间，生物传感器的响应时间的改进可能是生死攸关的问题。该项目将使制药行业受益，因为它将使所谓的手性药物更便宜，更安全，但手性药物的纯度问题在过去曾导致严重的副作用，如沙利度胺的悲惨案例。