权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Developmenth of the ultrasound device for thr preoperative lacalization of parathyroid tumor

甲状旁腺肿瘤术前定位超声装置的研制

基本信息

批准号：
60870057
负责人：
TAJIMA Atsushi
金额：
$ 3.2万
依托单位：
Hamamatsu University School of Medicine
依托单位国家：
日本
项目类别：
Grant-in-Aid for Developmental Scientific Research
财政年份：
1985
资助国家：
日本
起止时间：
1985 至 1987
项目状态：
已结题

项目摘要

We developed 3 types of mechanical sector scamer to predict the localization of parathyorid tumor:type I, II and III. Both of type and II are 7.5 MHz scanners;typeIII 10 MHz scanner. Type I had a 2 cn focal distance with water bag at the scanhead. The typeII consisted of a 3 cm focal distance and polyethylen protruding scanhead. On the other hand, the focal distance of typeIII (10 MHz) with water bag scanheas was 1 cm.All scanners were equiped with the ultrasonic real-time guidance system(Aloka SSD-125^r). Ultrasonographic investigations were performed in 6 cases of primary hyperparathyroidism (PHP) and 4 parients with secondary hyperparathyroidism (SHP). In these saces, computed tomography (CT) and scintigraphy(^<201> TL) were carried out,too.Among 3 types of scanner,typeII was mainly used,since this type gave the most clear picture and typell was operated easily. TypeII was namely the bast.Compared with conventinal electronic real-time linear scanner of 5 MHz,typell depicted more clearly abnormal parathyroid glands and could detect smaller senoma or hyperplasia.The predictability by ultrasonography (US),CT and RI was evaluated compared with operative findings,respctively. The preoperative localization of 6 parathyoid adenomas and 14 hypertrophied parathyroid glands were examined. In 4 parathyroid gland under 0.5g of weighr, the diagnostic accuracy of US was 75%, while that of CT was 50% and no gland was detected by RI. In 6 parathyroid gland from 0.5g to 1.0g the predictability was 50% by US,17%by CT and 33% by RI.As to 10 parathroid gland over 1.0g, the diagnotsic accuracy of US,CT,and RI was 90%,70%and 70%, respectively. US had the higher overall sensitivity than CT and RI. The minimum weight of the detectable parathyroid gland was 150mg,150mg and 500mg by US,CT and RI,respctively.Ultrasonography during the operation did not give the picture of parathyroid gland clearly. Similarly,the percutaneoud parathyroid diopsy guided by US was not successful.

我们研制了三种类型的机械扇形扫描仪来预测甲状旁腺肿瘤的定位：I型，II型和III型。型和II型均为7.5MHz扫描仪，III型为10 MHz扫描仪。I型具有2cn焦距，扫描头处带有水囊。Ⅱ型由焦距为3cm的聚乙烯探头组成。Ⅲ型（10 MHz）水囊式探头，焦距1cm，均配备AlokaSSD-125型实时超声引导系统。对6例原发性甲状旁腺功能亢进（PHP）和4例继发性甲状旁腺功能亢进（SHP）进行了超声检查。在3<201>种扫描仪中，以II型为主，因其图像最清晰，操作方便。与传统的5 MHz线阵扫描相比，Type 1能更清楚地显示异常甲状旁腺，并能检出较小的腺瘤或增生，与手术结果比较，评价超声、CT和RI对异常甲状旁腺的预测性。对6例甲状旁腺腺瘤和14例甲状旁腺肥大进行了术前定位检查。重量小于0.5g的4个甲状旁腺，超声诊断符合率为75%，CT诊断符合率为50%，RI未检出。6例甲状旁腺在0.5 ~ 1.0g范围内，超声诊断准确率为50%，CT诊断准确率为17%，RI诊断准确率为33%，10例1.0g以上的甲状旁腺，超声、CT和RI诊断准确率分别为90%，70%和70%。US的总体敏感性高于CT和RI。B超、CT、RI可检出甲状旁腺的最小重量分别为150 mg、150 mg、500 mg。同样，超声引导下经皮甲状旁腺镜检查也不成功。