Structural analysis of membrane proteins using template-mediated crystallization
Structural analysis of membrane proteins using template-mediated crystallization
批准号:
DP0556547
负责人:
Prof Benjamin Hankamer
金额:
$26.31万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2005
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2005-01-01 至 2008-06-30
中文摘要
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英文摘要
A new frontier technology will be developed in the form of a systematic crystallization pipeline for membrane proteins. This high throughput monolayer template technology is particularly suited for the structure determination of proteins that are otherwise difficult to crystallize and has clear commercial potential. Membrane protein structures are themselves of value to the biotechnology and pharmaceutical industry for targeted drug design, which could realise benefits in the form of novel medical treatments and reduced side effects. The monolayer template technology will also extend the capabilities of the National Cryo-EM facility, the infrastructure of which, is open for all Australian researchers.
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