INTRAFALLOPIAN PRESSURE (IFP) OF HUMAN AND RABBIT
INTRAFALLOPIAN PRESSURE (IFP) OF HUMAN AND RABBIT
批准号:
02454392
负责人:
ARAKI Tsutomu
金额:
$4.22万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (B)
财政年份:
1990
资助国家:
日本
项目状态:
已结题
起止时间:
1990 至 1992
中文摘要
我们发现输卵管内部有自己的压力。测定了人和家兔的输卵管内压(IFP)。并估计输卵管分泌物流速。人体IFP的测定。经颈将特氟龙导管(3法国尺寸)插入输卵管。在宫腔镜控制下,导管顶端精确放置在距子宫输卵管交界处1cm处。将含靛蓝胺的二氧化碳气体或生理盐水注入输卵管。CO_2和生理盐水的注射速度分别为30ml/min和4ml/min。注射压力以IFP测量。IFP被kimo-graphic记录。我们将宫腔镜血象插管试验(HKPT)命名为使用宫腔镜和CO2的IFP测量系统。该系统采用宫腔镜和生理盐水,并被命名为“宫腔镜KIMOGRAPHIC hydrotutuation TEST (HKHT)”。采用良好的专利人输卵管(n=16)进行HKPT和HKHT。受试者年龄29岁(±±)。[1] [a] [b] [b][]意为“……”2. 我…更多的测量兔子的IFP。选用雌性成年大白兔10只,体重2.5Kg。下腹部纵切口约3cm。并在阴道导管上加0.5 cm切口。聚四氟乙烯导管由阴道导管经子宫腔经腹插入输卵管。导管的顶部精确地放置在距UTJ 1厘米的位置。输卵管内注射含靛蓝碱的生理盐水。注射压力测量为IFP.3。家兔部分IFP测定。采用较细的聚四氟乙烯导管(外径0.5 mm,内径0.3 mm)。导管的顶部放置在输卵管的腹部、峡部或间质部。用Camino系统测定输卵管各部位的静止IFP。Camino系统是采用光纤传感器的计算机化压力测量系统。4. 测量家兔输卵管内半径及各部位长度。对家兔进行子宫输卵管造影,测量输卵管内腔半径和长度,测量输卵管内腔、输卵管峡部和输卵管间隙。5. 家兔输卵管分泌物流速的理论估计。F =[结果]1。人类的IFP。节律性收缩约6次/分。是由HKPT及HKHT录得。接触期IFP为103.1 ([SY.+-])。[) HKPT为3.8 mmHg, 84.8 mmHg (] SY.+-。[) HKHT 10.4 mmHg。舒张期IFP为86.6。[) HKPT为3.2 mmHg, 72.3 (] SY.+-。[) HKHT 2.4 mmHg准确的收缩次数/分钟。HKPT为5.8分,hkht为5.2分。IFP或兔子。家兔IFP为48.3 ([SY.+-])。[) 2.1mmHg。输卵管节律性收缩未见记录。3. 家兔部分IFP。兔输卵管腹、峡部和肠的IFP为0(0.05±±)。[) 0.5 mmHg, 25.2 (] SY.+-。[2] [j]张建平。[) 8.0 mmHg。4. 输卵管各部分的内半径和长度。腹、口、间质内半径分别为1.15 mm、0.55 mm、0.25 mm。腹、峡、间质长度为15.8(±±)。[) 3.3 mm, 43.7 (] SY.+-。[) 8.2 mm, 4.2 (] SY.+-。[)分别0.5mm。5. 输卵管分泌物流速的估计。家兔输卵管腔腹、峡部和间质处的输卵管分泌物流速分别为0、37.1、43.2 μ l。[讨论]这是关于IFP的第一份报告。本研究建立了IFP的概念。在HKPT和HKHT的IFP值之间观察到差异。这些测量系统使用喷射压力作为IFP。因此,IFP受注射速度和注射物质的影响。输卵管分泌物流速的真实值已由Gott报道。我们的值是Gott值的2倍。本研究中的流量由IFP、半径、长度和粘度获得。采用修正后的粘度值,流速值可能与Gott值相近。少
英文摘要
We discovered that oviduct has own pressure in the duct. We measured intrafallopian pressure (IFP) of human and rabbit. And we estimated flow rate of oviduct secrete.[METHOD]1. Measurement of IFP of human. Teflon catheter (3 french size) was transcervically inserted into oviduct. The top of the catheter was exactly placed at 1 cm inside from the uterotubal junction under hysteroscopic control. Carbon dioxide gas (CO_2) or saline with indigocarmine was injected into the oviduct. Injection speed of CO_2 and saline was 30ml/min, and 4ml/min, respectively. Injection pressure was measured as IFP.IFP was kimo-graphically recorded. We named THE HYSTEROSCOPIC KIMOGRAPHIC PNEUMOTUBATION TEST (HKPT) as IFP measuring system using hysteroscope and CO2. Also the system using hysteroscope and saline was named THE HYSTEROSCOPIC KIMOGRAPHIC HYDROTUBATION TEST (HKHT). The good patent human oviducts (n=16) were used for HKPT and HKHT.The age of the subjexts was 29 (〕SY.+-.〔) 4 (M (〕SY.+-.〔) S.E.). 2. Me … More asurement of IFP of rabbit. Female mature white rabbit (n=10, body weight=2.5Kg) was used. About 3 cm of longitudinal lower abdominal incision was carried out. And 0.5 cm incision was added into vaginal duct. Teflon ccatheter was transabdominally inserted from the vaginal duct into oviduct via uterine cavity. The top of the cathter was exactly placed at 1 cm inside from the UTJ.Saline with indigocarmine was injected into the oviduct. Injection pressure was measured as IFP.3. Measurement of partial IFP of rabbit. Thinner teflon cathter (outside diameter 0.5 mm, inside diameter 0.3 mm) was used. The top of the catheter was placed at amplla, isthmus, or interstitialis of the oviduct. And stationary IFP at each part of the oviduct was measureed with Camino system. Camino system is the computorized pressure measuringsystem with optic fiber transducer. 4. Measurement of inside radius and length of each part of oviduct of rabbit. Hystero-salpingo-graphy of rabbit was carried out in order to measure inside radius and length of amplla, istmus, and interstialis of oviduct. 5. Theoretical estimation of flow rate of oviduct secrete of rabbit. F=[RESULTS] 1. IFP of human. Rhythmical contraction about 6 times/min. was recoreded with HKPT and HKHT.IFP at contaction phase was 103.1 (〕SY.+-.〔) 3.8 mmHg by HKPT, and 84.8 (〕SY.+-.〔) 10.4 mmHg by HKHT.IFP at diastolic phase was 86.6 (〕SY.+-.〔) 3.2 mmHg by HKPT, and 72.3 (〕SY.+-.〔) 2.4 mmHg by HKHT.Exact contraction times/min. was 5.8 by HKPT, and 5.2 by HKHT.2. IFP or rabbit. IFP of rabbit was 48.3 (〕SY.+-.〔) 2.1mmHg. Rhythmical contraction of the oviduct was not recorded. 3. Partial IFP of rabbit. The IFP of the amplla, isthums, and intestitialis of rabbit oviduct was 0 (〕SY.+-.〔) 0.5 mmHg, 25.2 (〕SY.+-.〔) 2.2 mmHg, 69.2 (〕SY.+-.〔) 8.0 mmHg, respectively. 4. inside radius and length of each part of the oviduct. Inside radius of amplla, istumus, and interstitialis was 1.15 mm, 0.55 mm, 0.25 mm, respectively. And the length of amplla, isthmus, and interstitialis was 15.8 (〕SY.+-.〔) 3.3 mm, 43.7 (〕SY.+-.〔) 8.2 mm, 4.2 (〕SY.+-.〔) 0.5mm, respectively. 5. Estimation of flow rate of fallopian secrete. The flow rate of the fallopian secrete/hr at amplla, isthmus, and interstitialis of the oviduct of rabbit was estimated as 0 mul, 37.1 mul, 43.2 mul, respectively.[DISCUSSIONS] This is the first report on IFP.The concept of IFP is established in this study. Difference was observed between IFP values by HKPT and HKHT.These measuring system use injection pressure as IFP.Therefore, IFP was affected by injection speed and injection substances. Real value of flow rate of the oviduct secrete was already reported by Gott. Our value was 2 times higher than Gott's value. Flow rate in this study was obtained from IFP, radius, length, and viscosity. Corrected value of viscosity is used, the flow rate value is probably similar with Gott's value. Less
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可世木久幸、明楽重夫、荒木 勤: "ヒトおよび実験動物の卵管内圧測定法の開発" 日本受精着床学会雑誌. 9巻. 270-273 (1992)
Hisayuki Kayogi、Shigeo Akira、Tsutomu Araki:“开发测量人类和实验动物输卵管内压力的方法”,日本受精与植入学会杂志,第 9 卷,270-273(1992 年)。
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可世木 久幸: "不妊" 日本産科婦人科学会関東連合地方部会会報. 52. 89-91 (1990)
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可世木 久幸・明楽 重夫・荒木 勤: "産婦人科不妊領域における腹腔鏡の新しい試み" 産婦人科の世界. 43(3). (1991)
Hisayuki Kayogi、Shigeo Akira 和 Tsutomu Araki:“腹腔镜检查在妇产科不孕症领域的新试验”《妇产科世界》43(3) (1991)。
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S.Akira,A.Sanbuissho,Y.C.Lin,T.Araki: "Acceleration of Embyro transport in superovulated Adult Rats" Life Scicnces. vol.53. 1243-1251 (1993)
S.Akira,A.Sanbuissho,Y.C.Lin,T.Araki:“超排卵成年大鼠胚胎运输的加速”生命科学。
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S.Akira, A.Sanbuissho, Y.C.Lin, and T.Araki: "ACCLERATION OF EMBRYO TRANSPORT IN SUPEROVULATED ADULT RATS" Life Sciences. Vol.53-15. 1243-1251 (1993)
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