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BRAIN TEMPERATURE AND BRAIN DAMAGE INDUCTION DURING BRAIN ISCHEMIA AND HYPOXIA IN FETAL SHEEP.

BRAIN TEMPERATURE AND BRAIN DAMAGE INDUCTION DURING BRAIN ISCHEMIA AND HYPOXIA IN FETAL SHEEP.
胎羊脑缺血和缺氧期间的脑温度和脑损伤诱导。
批准号:
09557133
负责人:
ARAKI Tsutomu
金额:
$5.12万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
1997
资助国家:
日本
项目状态:
已结题
起止时间:
1997 至 1999

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中文摘要
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英文摘要
[PURPOSE] The purpose of this study is to evaluate the relationship between changes in brain temperature and induction of brain damage during brain ischemia and hypoxia in fetal sheep.[METHOD] We inducted fetal brain ischemia and hypoxia, then measured brain temperature and induction of brain damage in six chronically instrumented fetal sheep.[RESULTS] Fetal brain hypoxia and ischemia elicited brain damage, which was partially diminished by the slow induction of mild hypothermia.[CONCLUSION] The slow induction of mild hypothermia prevents the induction of fetal brain damage during brain ischemia and hypoxia in fetal sheep.
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Yoneyama Y, et al: "Evidence for mechanisms of acute phase response to endotoxin in late-gestation fetal goats"Am J. Obstet Gynecol. 179. 750-755 (1998)
Yoneyama Y 等人:“妊娠晚期胎儿山羊对内毒素的急性期反应机制的证据”Am J. Obstet Gynecol。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
S.Suzuki, et al.: "Role of adenosine in regulation of brain temperature in fetal sheep" Am.J.Obstet Gynecol. 181 in printing. (1999)
S.Suzuki 等人:“腺苷在调节胎羊脑温度中的作用”Am.J.Obstet Gynecol。
DOI: --
发表时间:
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作者: []
通讯作者:
R.Sawa: "Fetal plasma hypoxanthine level in growth-retarded fetuses before labor" J.Clin.Endocrinol.Metab.82・12. 4028-4031 (1997)
R.Sawa:“分娩前生长迟缓胎儿的胎儿血浆次黄嘌呤水平”J.Clin.Endocrinol.Metab.82・12 4028-4031(1997)。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
Yoneyama Y. et al: "Plasma adenosine levels increase in normal pregnant women"Am. J Obstet. Gynecol. (印刷中). (2000)
Yoneyama Y. 等人:“正常孕妇的血浆腺苷水平增加”Am. Gynecol (2000 年出版)。
DOI: --
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通讯作者:
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