Small radius artificial blood vessel with a high endothelial reorganization effect by static magnetic stray field from ferrite coating

点击翻译按钮获取中文摘要

Basic knowledges required for fabricating artificial blood vessel with ferrite coating on their inner wall were investigated ; the leakage flux from the ferrite coating is expected to enhance the endothelial reorganization, and, therefore, supress thrombi. Sheets of expanded polytetrafluoroethylene (EPTFE) membrane were exposed to an rf air plasma on which magnetite (Fe_3O_4) coating was successfully deposited by ferrite plating ; the rf plasma increases the wettability of the surface of the EPTFE.By exposing the surface of the EPTFE sheet which is dipped in an aqueous solution of H_3BO_3, the wettability was increased further more, and Fe_3O_4 coating of finer grains were successfully deposited. By in viva experiments on dogs revealed that the biocompatibility of the ferrite-coated EPTFE sheets are nearly equal to that of the uncoated sheets. To reveal the enhancement of the endothelial reorganization effect, further experiments are needed.