Materials World Network: Self-Assembled DNA Nanotubes: Biomimetic Design, Controlled Surface Alignment and Templated Nanowire Formation

材料世界网络：自组装 DNA 纳米管：仿生设计、受控表面排列和模板化纳米线形成

• 批准号: 43332450
• 负责人: Professor Dr. Michael Mertig
• 金额: --
• 依托单位: Professur für Physikalische Chemie, Mess- und Sensortechnik
• 依托单位国家: 德国
• 项目类别: Research Grants
• 财政年份: 2007
• 资助国家: 德国
• 起止时间: 2006-12-31 至 2010-12-31
• 项目状态: 已结题
• 来源: https://gepris.dfg.de/gepris/projekt/43332450?language=en
• 关键词: Materials; World; Network; Self; Assembled

The co-PIs Yan and Mertig will coordinate the management of the project and monitor the research progress. While email exchange will happen between the two co-PIs on a daily basis, regular biweekly meetings between the two groups will be held through tele-video-conference. Tasks will be assigned to the two groups to avoid any overlapping efforts. The Yan group will be in charge of the design, selfassembly and characterization of a group of spiral DNA tubes. The Mertig groups will be in charge of the measurement of the mechanical properties of the DNA tubes, surface alignment and metallization of various DNA nanotubes (including the newly designed spiral tube and previously reported DNA tubes). Knowledge gained from either side will be transfer between the two groups to ensure the reproducibility of the results and efficient implementation of improved designs. To achieve an efficient and fruitful international collaboration, we plan to exchange graduate students between the two laboratories. We plan to send students to each other’s lab twice a year. Budget for student travel has been requested. Table below lists major milestones for the proposed research. Y1 A: Design, of spiral DNA nanotubes with controlled diameter, helical pitch and helical chirality (Yan); B:Structure characterization of the tubes: AFM (Yan), TEM and cryo-TEM (Mertig); C: Use of the initiallyachieved spiral tubes as templates for metallization (Mertig).Y2 A: Optimize the growth of spiral DNA tubes to increased length (Yan); B: Measure the flexural rigidity of the spiral DNA tubes. (Mertig); C: Align various DNA nanotubes into 2D networks (Yan & Mertig) and improve the metallization of DNA tubes with different metals (Mertig).Y3 A: Decoration of the tube with nanoclusters with controlled geometries (Yan & Mertig); B: Structural and electrical characterization of the hybrid structures (Mertig)

合作PI Yan和Mertig将协调项目的管理并监督研究进展。虽然两个联合PI之间每天都会进行电子邮件交流，但两个小组之间的定期双周会议将通过电视会议举行。将向这两个小组分配任务，以避免工作重叠。Yan团队将负责一组螺旋DNA管的设计、自组装和表征。Mertig小组将负责测量DNA管的机械性能，各种DNA纳米管的表面排列和金属化（包括新设计的螺旋管和以前报道的DNA管）。从任何一方获得的知识将在两个小组之间转移，以确保结果的可重复性和改进设计的有效实施。为了实现高效和富有成效的国际合作，我们计划在两个实验室之间交换研究生。我们计划一年两次让学生互相参观实验室。已申请学生旅行预算。下表列出了拟议研究的主要里程碑。Y1 A：设计具有可控直径、螺距和螺旋手性的螺旋DNA纳米管（Yan）; B：管的结构表征：AFM（Yan）、TEM和cryo-TEM（Mertig）; C：使用最初获得的螺旋管作为金属化的模板（Mertig）。Y2 A：优化螺旋DNA管的生长以增加长度（Yan）; B：测量螺旋DNA管的抗弯刚度。（Mertig）;丙：将各种DNA纳米管排列成2D网络（Yan & Mertig）并用不同的金属改善DNA管的金属化（Mertig）。Y3 A：用具有受控几何形状的纳米团簇装饰管（Yan & Mertig）; B：混合结构的结构和电学表征（Mertig）