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Dynamic Property of Intermediate Filaments : Regulation by Phosphorylation

Dynamic Property of Intermediate Filaments : Regulation by Phosphorylation
中间丝的动态特性:磷酸化的调节
批准号:
06454681
负责人:
INAGAKI Masaki
金额:
$3.9万
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (B)
财政年份:
1994
资助国家:
日本
项目状态:
已结题
起止时间:
1994 至 1995

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中文摘要
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英文摘要
Site-specific phosphory lation of intermediate filament (IF) proteins on serine and threoninc residues leads to alteration of the filament structure, in vitro and in vivo, Protein kinases involved in cell signaling and those activated in mitosis dynamically control spatial and temporal organization of intracellular IF phosphorylation.Thus, IF phosphorylation appears to be one of the most predominant stratogy to coordinate intracellular organization of the IF network.
期刊论文(52)
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通讯作者:
Tsurumi, C. et al.: "Degradation of c-Fos by the 26S Proteasome is accelerated by c-Jun and multiple protein kinases." Mol. Cell. Biol.15. 5682-5687 (1995)
Tsurumi, C. 等人:“c-Jun 和多种蛋白激酶加速了 26S 蛋白酶体对 c-Fos 的降解。”
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16
    Elucidation of new functions of intermediate filaments linking a relationship between proliferation and differentiation
    • 批准号:
      23247035
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $18.8万
    • 财政年份:
      2011
    • 负责人:
      INAGAKI Masaki
    • 依托单位:
    Antinomy of cell-cell adhesion and cell proliferation
    • 批准号:
      20370082
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $13.31万
    • 财政年份:
      2008
    • 负责人:
      INAGAKI Masaki
    • 依托单位:
    Elucidation of the protein phosphorylation signaling and the regulatory mechanism of cytoskeleton
    • 批准号:
      18370085
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.28万
    • 财政年份:
      2006
    • 负责人:
      INAGAKI Masaki
    • 依托单位:
    Regulatory mechanisms of cytoskeletal proteins by phosphorylation and their cellular functions
    • 批准号:
      16370092
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $10.11万
    • 财政年份:
      2004
    • 负责人:
      INAGAKI Masaki
    • 依托单位:
    国内基金
    海外基金
    原生动物四膜虫生殖小核(germline nucleus)体功能(somatic function)的分子基础研究