RP2: Transfer from goal-directed behavior to stimulus-response habits and its modulation by acute stress in gaming disorder and buying-shopping disorder

RP2：从目标导向行为到刺激反应习惯的转变及其在游戏障碍和购买购物障碍中的急性压力的调节

• 批准号: 444977161
• 负责人: Professorin Dr. Astrid Müller
• 金额: --
• 依托单位: Lehrstuhl für Klinische Psychologie und Psychotherapie
• 依托单位国家: 德国
• 项目类别: Research Units
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/444977161?language=en
• 关键词: RP2; Transfer; goal; directed; behavior

The ability of conditioned stimuli to affect instrumental responding is a robust finding from animal as well as human research and is considered a key factor for the development and maintenance of addictive behaviors. In Internet use disorders, Pavlovian conditioning processes are thought to intensify motivational responses, which can activate instrumental reward seeking. However, there is very limited knowledge on the impact of conditioned cues on instrumental responding and of factors that affect these processes (e.g. acute stress) in individuals with risky or problematic use of specific Internet applications. While there is evidence that acute stress may trigger relapse in addictions, no study to date has investigated the effect of acute stress on the impact of conditioned cues on instrumental responding in individuals at risk for Internet use disorders. The aim of this project is to investigate the impact of conditioned stimuli on instrumental responding and possible effects of acute stress in early stages of gaming disorder and buying-shopping disorder. The project will include four groups (each with 64 participants): individuals with 1) risky use of games, 2) risky use of shopping applications, 3) non-problematic use of games, 4) non-problematic use of shopping applications. After completion of the diagnostics including the experimental and neuropsychological tasks of the core battery, a Pavlovian-Instrumental-Transfer (PIT) paradigm with stimuli and rewards related to gaming or buying-shopping will be used. In the Pavlovian training phase, two neutral stimuli will be paired either with gaming- or with buying-shopping stimuli. In the second phase, participants learn to perform different key presses to achieve gaming- or buying-shopping-related rewards. In the transfer phase, the conditioned stimuli from the Pavlovian training phase will be presented while the instrumental responses can be performed as before. An outcome devaluation will be implemented after the first half of the transfer phase. The role of acute stress will be investigated using the standardized Trier Social Stress Test, which will be administered after acquisition of the conditioned responses and learning of instrumental behavior. Reward expectancy ratings and attention allocation to the different experimental stimuli assessed with an eye-tracker will indicate conditioned responses while response choice and response rate indicate instrumental behavior. RP2 has strong synergies with RP3 and RP6, which will also investigate facets of cue reactivity. Furthermore, RP2 is connected to RP4, which will also address cue reactivity and acute stress. There are also synergies between RP2 and RP5, as both projects will investigate buying-shopping disorder and effects of acute stress.

条件刺激影响工具反应的能力是动物和人类研究的强大发现，被认为是成瘾行为发展和维持的关键因素。在互联网使用障碍中，帕夫洛维亚的调节过程被认为可以加强动机反应，从而激活寻求工具的奖励。但是，关于条件线索对有风险或有问题使用特定互联网应用程序的人的这些过程（例如急性压力）的因素的影响以及影响这些过程（例如急性压力）的因素的知识非常有限。虽然有证据表明急性压力可能会引发成瘾的复发，但迄今为止，尚无研究调查急性压力对条件线索对有互联网使用障碍风险的个体的工具反应的影响的影响。该项目的目的是研究条件刺激对游戏障碍和购买购物障碍早期急性压力的工具反应和急性压力的影响的影响。该项目将包括四个组（每人有64名参与者）：具有1）风险使用游戏的个人，2）危险使用购物申请，3）非问题使用游戏，4）非问题使用购物应用程序。诊断完成后，将使用核心电池的实验和神经心理学任务，将使用带有刺激和与游戏或购买购物有关的刺激和奖励的Pavlovian-insunstrumental-Transfer（PIT）范式。在Pavlovian训练阶段，将将两个中性刺激与游戏或购买购物刺激配对。在第二阶段，参与者学习执行不同的关键压力机以获得游戏或购买购物相关的奖励。在转移阶段，将提出来自Pavlovian训练阶段的条件刺激，同时可以像以前一样进行仪器响应。转移阶段上半年将实施结果贬值。急性应力的作用将使用标准化的TRIER社会压力测试进行研究，该测试将在获得条件响应和学习工具行为后进行管理。奖励预期评分和对用眼球评估的不同实验刺激分配的注意力分配将表明有条件的响应，而响应选择和响应率表示工具行为。 RP2与RP3和RP6具有很强的协同作用，这也将研究提示反应性的方面。此外，RP2连接到RP4，这也将解决提示反应性和急性应力。 RP2和RP5之间也存在协同作用，因为这两个项目都将研究购买购物障碍和急性压力的影响。