The pursuit of conservative dental treatment design in a new era by diverse utilization of an antibacterial monomer

在本研究项目中，对抗菌单体MDPB用于牙科保守领域各种治疗方式的可能性进行了研究。结果表明，含MDPB的牙本质粘接系统在直接盖髓治疗中能有效地保持牙髓活力。通过加入MDPB，成功地制备了抗菌根管充填系统、多功能粘接调节剂和封闭树脂的原型。此外，未证实口腔细菌对MDPB产生耐药性，表明使用MDPB作为抗菌剂的益处。

In this research project, the possibility of utilization of an antibacterial monomer MDPB for various treatment modalities in the field of conservative dentistry was examined. It was found that MDPB-containing dentin bonding system was effective to preserve pulp vitality in direct pulp capping therapy. The prototypes of antibacterial root canal filling system, multi-purpose conditioning agent for adhesion, and sealing resin were successfully achieved by incorporation of MDPB. In addition, no development of resistance against MDPB by oral bacteria was confirmed, suggesting the benefits of usage of MDPB as the antimicrobial.