Molecular mechanisms of ovarian differentiation induced by sex hormones
Molecular mechanisms of ovarian differentiation induced by sex hormones
批准号:
20247004
负责人:
NAGAHAMA Yoshitaka
金额:
$31.28万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2011
中文摘要
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英文摘要
Molecular mechanisms of sex hormone-induced ovarian differentiation were investigated in two fishes (medaka and tilapia). Our results show that estrogen (E2) induces ovarian differentiation by acting through estrogen receptors (β2 and β1) and R-spondin1. We also suggest that P450c17-II (a steroidogenic enzyme necessary for the production of DHP, maturation-inducing hormone of fish) is involved in the initiation of meiosis in both XX and XY fish.
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R-spondin1 is essential for ovarian differentiation in fish
R-spondin1 对于鱼类卵巢分化至关重要
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Zhou, L.Y., T. Chakraborty, Wang, D.S. and Nagahama, Y]
通讯作者:
Y
Ovarian estrogens are critical for the suppression of male sexual behavior in adult female Japanese medaka, Oryzias latipes
卵巢雌激素对于抑制成年雌性日本青鳉(Oryzias latipes)的雄性性行为至关重要
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Paul-Prasanth, B., Nagahama, Y.]
通讯作者:
Y.
Endocrine regulation of oogenesis in the medaka, Oryzias latipes. In "Medaka : A Model for Organogenesis, Human Disease and Evolution" (H. Takeda et al. eds.
青鳉、Oryzias latipes 卵子发生的内分泌调节。
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Shibata, N., Nakamoto, M., Shibata, Y. and Nagahama, Y.]
通讯作者:
Y.
Sex determination in fishes(Vol.1)("Hormones and Reproduction of Vertebrates")
鱼类的性别决定(第一卷)(“激素与脊椎动物的繁殖”)
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[Paul-Prasanth, B., Nakamura, M., Nagahama, Y.]
通讯作者:
Y.
Expression of a lyasedeficient Cyp17 in the fish head kidney
裂解酶缺陷型 Cyp17 在鱼头肾中的表达
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Nagahama, Y.]
通讯作者:
Y.
共 30 条
Molecular mechanisms of sexual plasticity in adult medaka gonads
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批准号:24370028
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.32万
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财政年份:2012
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负责人:NAGAHAMA Yoshitaka
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依托单位:
Mechanisms of sex determination and gonadal sex differentiation in fish
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批准号:16086213
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$47.87万
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财政年份:2004
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负责人:NAGAHAMA Yoshitaka
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依托单位:
Molecular Mechanisms of Sex Change in Fish
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批准号:16370032
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.54万
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财政年份:2004
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负责人:NAGAHAMA Yoshitaka
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依托单位:
Functions and Mechanisms of Action of the Medaka Sex-Determining Gene
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批准号:14340259
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.02万
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财政年份:2002
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负责人:NAGAHAMA Yoshitaka
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依托单位:
Molecular mechanisms of gamete maturation-inducing hormone synthesis
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批准号:10440247
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.55万
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财政年份:1998
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负责人:NAGAHAMA Yoshitaka
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依托单位:
Molecular mechanisms of oocyte and sperm maturation-inducing hormone
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批准号:08454266
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$5.06万
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财政年份:1996
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负责人:NAGAHAMA Yoshitaka
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依托单位:
Molecular Mechanisms of Germ Cell Formation
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批准号:07283104
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$190.34万
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财政年份:1995
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负责人:NAGAHAMA Yoshitaka
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依托单位:
Molecular Mechanisms of Sex Determination and Differentiation
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批准号:06044235
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$7.74万
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财政年份:1994
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负责人:NAGAHAMA Yoshitaka
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依托单位:
Molecular mechanisms of activin B-induced spermatogenesis
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批准号:06454022
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.35万
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财政年份:1994
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负责人:NAGAHAMA Yoshitaka
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依托单位:
General principle involved in the mechanism of oocyte maturation
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批准号:04044177
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$4.86万
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财政年份:1992
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负责人:NAGAHAMA Yoshitaka
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依托单位:
M/lecular regulation of germ cell formation
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批准号:02102010
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项目类别:Grant-in-Aid for Specially Promoted Research
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资助金额:$112.0万
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财政年份:1990
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负责人:NAGAHAMA Yoshitaka
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依托单位:
海外基金