The analysis of the differentiation and function of the cells in central nervous system regulated by endoplasmic reticulum stress response.
The analysis of the differentiation and function of the cells in central nervous system regulated by endoplasmic reticulum stress response.
批准号:
22800049
负责人:
SAITO Atsushi
金额:
$2.01万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Research Activity Start-up
财政年份:
2010
资助国家:
日本
项目状态:
已结题
起止时间:
2010 至 2011
中文摘要
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英文摘要
We revealed that the differentiation of neural precursor cells into astrocytes or neurons was delayed by OASIS or BBF2H7 deficiency. We tried to identify the target genes of transcription factors OASIS and BBF2H7. Consequently, we identified the direct target genes of OASIS in central nervous system. Further, we revealed that the acceleration of the differentiation of neural precursor cells into astrocytes by the signaling from OASIS mediated the epigenetic regulation which promoted the demethylation of the promoter region of astrocyte-specific marker genes.
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小胞体ストレス応答による生体機能調節機構の解析
内质网应激反应生物功能调节机制分析
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[齋藤敦, 今泉和則]
通讯作者:
今泉和則
小胞体ストレスセンサー群によるアストロサイト分化制御の分子機構
内质网应激传感器控制星形胶质细胞分化的分子机制
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[齋藤敦, 浅田梨絵, 佐野坂司, 中島欽一, 今泉和則]
通讯作者:
今泉和則
DOI:
10.1074/jbc.m111.332593
发表时间:
2012-03-09
期刊:
JOURNAL OF BIOLOGICAL CHEMISTRY
影响因子:
4.8
作者:
[Asada, Rie, Saito, Atsushi, Imaizumi, Kazunori]
通讯作者:
Imaizumi, Kazunori
DOI:
10.1074/jbc.m110.152900
发表时间:
2011-02-11
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
[Saito A, Ochiai K, Kondo S, Tsumagari K, Murakami T, Cavener DR, Imaizumi K]
通讯作者:
Imaizumi K
転写因子OASISによる大腸粘膜における杯細胞の分化制御
转录因子 OASIS 对结肠粘膜杯状细胞分化的调节
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[浅田梨絵, 齋藤敦, 近藤慎一, 金本聡自, 今泉和則]
通讯作者:
今泉和則
共 28 条
Development of 100 W-class superconducting transmit filter
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批准号:24560393
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.41万
-
财政年份:2012
-
负责人:SAITO Atsushi
-
依托单位:
The elucidation of the pathogenesis of dysphagia in amyotrophic lateral sclerosis -Using model mice-
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批准号:23791921
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项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.16万
-
财政年份:2011
-
负责人:SAITO Atsushi
-
依托单位:
New therapeutic strategy with SMTP for acute cerebral ischemia
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批准号:23791582
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.66万
-
财政年份:2011
-
负责人:SAITO Atsushi
-
依托单位:
A study on the mechanisms involved in the invasion of host cells by periodontal pathogens and the novel method for its regulation
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批准号:22592317
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.25万
-
财政年份:2010
-
负责人:SAITO Atsushi
-
依托单位:
Development of high-performance transmit filter using superconducting bulk
-
批准号:21760246
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.66万
-
财政年份:2009
-
负责人:SAITO Atsushi
-
依托单位:
Expression of cellular protective factors in neuronal cells after cerebral ischemia
-
批准号:21791344
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.75万
-
财政年份:2009
-
负责人:SAITO Atsushi
-
依托单位:
The discovery research of the vulnerability factor, which is associated with schizophrenia, through familial clustering cases of both Hermansky-Pudlak syndrome and schizophrenia.
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批准号:20790857
-
项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.66万
-
财政年份:2008
-
负责人:SAITO Atsushi
-
依托单位:
Study on the pathogenecity of tuberculosis in elderly people and development of its prevention
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批准号:15591061
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2003
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负责人:SAITO Atsushi
-
依托单位:
Study on the pathogenesis of normal flora in respiratory tract infection and on the diagnostic methods for the flora
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批准号:10670555
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.66万
-
财政年份:1998
-
负责人:SAITO Atsushi
-
依托单位:
Studies on newly synthesized peptides having parasitocidal activity, and their mechanisms on host immune repsponses.
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批准号:07406014
-
项目类别:Grant-in-Aid for Scientific Research (A)
-
资助金额:$23.04万
-
财政年份:1995
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负责人:SAITO Atsushi
-
依托单位:
Studies on the Induction of Immune Cells and Activating Mechanisms by Substances Derived from Oxoplasma Bgondii
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批准号:63480087
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项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.48万
-
财政年份:1988
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负责人:SAITO Atsushi
-
依托单位:
Study on Development of New Methods in the Treatment of Infection Caused by Intracellular Multiplied Bacteria
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批准号:61480198
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$2.11万
-
财政年份:1986
-
负责人:SAITO Atsushi
-
依托单位:
国内基金
海外基金
PDGF-BB/OASIS塑造肿瘤基质微环境促未分化甲状腺癌发生发展的作用及机制
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批准号:--
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项目类别:面上项目
-
资助金额:52万元
-
批准年份:2022
-
负责人:葛明华
-
依托单位:
OASIS 转录激活胶原信号驱动未分化甲状腺癌恶性表型的作用及机制
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批准号:LY22H160036
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项目类别:省市级项目
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资助金额:--
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批准年份:2021
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负责人:谭卓
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依托单位:
lncRNA-Hser通过Oasis调控HIBD新生小鼠脑内胶质微环境的作用研究
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批准号:81871196
-
项目类别:面上项目
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资助金额:57.0万元
-
批准年份:2018
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负责人:刘倩
-
依托单位: