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Search for the biologically active substances from the marine invertebrates in the Caribbean

Search for the biologically active substances from the marine invertebrates in the Caribbean
从加勒比海海洋无脊椎动物中寻找生物活性物质
批准号:
15404010
负责人:
TSUKAMOTO Sachiko
金额:
$4.99万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2003
资助国家:
日本
项目状态:
已结题
起止时间:
2003 至 2004

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中文摘要
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英文摘要
The marine environment has proven to be a rich source of extremely potent compounds that have demonstrated significant activities in antitumor, antiinflammatory, analgesia, immunomodulation, allergy, and antiviral assays. Especially, the marine invertebrates in the Caribbean afforded the variety of compounds. Among them ecteinascidin 743 was known to be an antitumor compound. In this project we collected marine invertebrates in the Caribbean and prepared samples for screening of drug discovery.
期刊论文(22)
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会议论文
DOI: 10.1016/j.bmcl.2003.10.053
发表时间: 2004-01-19
期刊: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
影响因子: 2.7
作者: [Tsukamoto, S, Miura, S, Ohta, T]
通讯作者: Ohta, T
Sachiko Tsukamoto: "New Polyhydroxy Sterols : Proteasome Inhibitors from a Marine Sponge Acanthodendrilla sp."J.Nat.Prod. 66(9). 1181-1185 (2003)
Sachiko Tsukamoto:“新的多羟基甾醇:来自海洋海绵 Acanthodendrilla sp 的蛋白酶体抑制剂。”J.Nat.Prod。
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通讯作者:
Sachiko Tsukamoto: "Three New Cytotoxic Sesterterpenes from a Marine Sponge Spongia sp."J.Nat.Prod.. 66(3). 438-440 (2003)
Sachiko Tsukamoto:“来自海洋海绵 Spongia sp. 的三种新的细胞毒性倍半萜。”J.Nat.Prod.. 66(3)。
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DOI: 10.1021/np020497l
发表时间: 2003-03-01
期刊: JOURNAL OF NATURAL PRODUCTS
影响因子: 5.1
作者: [Tsukamoto, S, Miura, S, Ohta, T]
通讯作者: Ohta, T
9
    Research on the marine sources for drug discovery in the tropical coral reef.
    • 批准号:
      22406001
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $12.23万
    • 财政年份:
      2010
    • 负责人:
      TSUKAMOTO Sachiko
    • 依托单位:
    Search for Natural Products which Enhance the Function of TumorSuppressor Protein and Study of the Mechanisms of Effects
    • 批准号:
      22310138
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $12.73万
    • 财政年份:
      2010
    • 负责人:
      TSUKAMOTO Sachiko
    • 依托单位:
    Search for Natural Products Which Enhance the Effect of Tumor Suppressor Protein
    Investigation of physiology, ecology, and constituents in the invertebrates, which inhabit in the coral reef of the North Pacific
    海外基金