Amino acid transporters and the chloroquine resistance transporter of the intracellular malaria parasite

细胞内疟原虫的氨基酸转运蛋白和氯喹抗性转运蛋白

• 批准号: DP0559433
• 负责人: Prof Kiaran Kirk
• 金额: $ 18.38万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0559433
• 关键词: Amino; acid; transporters; chloroquine; resistance

This work entails an ongoing collaboration between three independent research groups with highly complementary expertise and experience. It will make a significant contribution to the maintenance of Australia's scientific capabilities and training opportunities. The project will yield important insights into the biology of the causative agent of a major human disease, and the mechanism by which the malaria parasite has developed resistance to antimalarial drugs. Although not yet endemic in Australia, malaria is a serious problem in the local region and this work will help Australia meet its obligations to carry out high-quality research that advances our knowledge in this area.

这项工作需要三个具有高度互补的专门知识和经验的独立研究小组之间的持续合作。 它将对保持澳大利亚的科学能力和培训机会作出重大贡献。 该项目将对人类重大疾病病原体的生物学以及疟疾寄生虫对抗疟药物产生抗药性的机制产生重要见解。 虽然疟疾在澳大利亚尚未流行，但在当地是一个严重问题，这项工作将有助于澳大利亚履行其义务，开展高质量的研究，增进我们在这一领域的知识。