Herbicide Decomposition Polymers Prepared by Molecular Imprinting

分子印迹制备除草剂分解聚合物

• 批准号: 13555227
• 负责人: TAKEUCHI Toshifumi
• 金额: $ 8.83万
• 依托单位: Kobe University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-13555227/
• 关键词: Molecular Imprinting; Molecular Recognition; Catalysts; Combinatorial Chemistry

Atrazine imprinted synthetic polymers were prepared with a combined use of binding (methacrylic acid) and catalytic (2-sulfoethyl methacrylate) functional monomers, in which atrazine and other 6-chloro triazine herbicides were bound and converted to less toxic compounds. A chloride at the 6-position was converted to a methoxy group by the polymer in a methanol-containing solvant, where the imprinting effects enhanced the catalytic activity. Competitive inhibition of the atrazine transformation was observed in the presence of a structurally related binder, ametryn, suggesting that the catalytic reaction proceeded in the binding sites generated by the molecular imprinting process.

将阿特拉津和其他6-氯三嗪除草剂键合在一起，转化为毒性较低的化合物，通过键合(甲基丙烯酸)和催化(甲基丙烯酸磺乙酯)功能单体的组合，制备了阿特拉津印迹合成聚合物。在含有甲醇的溶剂中，聚合物将6位的氯离子转化为甲氧基，印迹效应增强了催化活性。在结构相关的粘结剂ametryn的存在下，阿特拉津的转化受到竞争抑制，这表明催化反应是在分子印迹过程中产生的结合部位进行的。

项目成果

Ikegami, T.: "Bisphenol A-recognition Polymers Prepared by Covalent Molecular Imprinting"Anal.Chim.Acta. 504. 131-135 (2004)

Ikegami, T.：“通过共价分子印迹制备双酚 A 识别聚合物”Anal.Chim.Acta。

Takeuchi, T., Fukuma, D., Matsui, J., Mukawa, T.: "Combinatorial Molecular Imprinting for Formation of Atrazine Decomposing Polymers"Chem. Lett.. 530-531 (2001)

Takeuchi, T.、Fukuma, D.、Matsui, J.、Mukawa, T.：“用于形成莠去津分解聚合物的组合分子印迹”Chem。

Takeuchi, T., Fukuma, D., Matsui, J., Mukawa, T.: "Combinatorial Molecular Imprinting for Formation of Atrazine Decomposing Polymers"Chem.Lett.. 530-531 (2001)

Takeuchi, T.、Fukuma, D.、Matsui, J.、Mukawa, T.：“用于形成莠去津分解聚合物的组合分子印迹”Chem.Lett.. 530-531 (2001)

Ikegami, T., Mukawa, T., Nariai, H., Takeuchi, T.: "Bisphenol A-recognition Polymers Prepared by Covalent Molecular Imprinting"Anal.Chim.Acta. 504. 131-135 (2004)

Ikegami, T.、Mukawa, T.、Nariai, H.、Takeuchi, T.：“通过共价分子印迹制备的双酚 A 识别聚合物”Anal.Chim.Acta。

Kubo, H., Nariai, H., Takeuchi, T.: "Multiple Hydrogen Bonding-based Fluorescent Imprinted Polymers for Cyclobarbital Prepared with 2,6-Bis(acrylamido)pyridine"Chem.Commun. 2792-2793 (2003)

Kubo, H.、Nariai, H.、Takeuchi, T.：“用 2,6-双（丙烯酰胺）吡啶制备环巴比妥的多重氢键荧光印迹聚合物”Chem.Commun。