Synergetic Molecular Recognition Sites having a Signaling Function Prepared by Molecular Imprinting

使用可聚合金属卟啉和/或甲基丙烯酸作为功能单体制备杂环化合物的信号印迹聚合物，并通过色谱测试、Scatchard分析和光谱分析进行评价。在聚合物中，金属卟啉残基和甲基丙烯酸残基在印迹结合位点协同作用。印迹聚合物的吸光度与目标分子浓度的对数呈线性关系，表明该聚合物可作为目标分子的选择性传感材料。各种金属卟啉可用作功能化单体，以制备能够与金属卟啉配位的各种目标化合物的信号印迹聚合物。

Signaling-imprinted polymers were prepared for heterocyclic compounds using a polymerizable metalloporphyrin and/or methacrylic acid as functional monomer(s), and evaluated by chromatographic tests, Scatchard analysis, and spectroscopic analysis. In the polymers, the metalloporphyrin residue and methacrylic acid residues worked cooperatively at the imprinted binding site. A linear relationship was observed between the UV-Vis absorbance of the imprinted polymer and the logarithm of target concentrations, indicating that the polymer may be used as a selective sensing material for the given target molecule. Various metalloporphyrins can be used as functionalized monomers in order to prepare signaling-imprinted polymers for a wide range of target compounds capable of coordination with metalloporphyrins.