PRIMARY PREVENTION OF LIFE-STYLE RELATED DISEASES FOR YOUNG ; AIM FOR OPTIMIZED INTERVENTION STRATEGY

最近，与生活方式相关的疾病有增加和年轻化的趋势。我们从1980年开始充分利用健康体检预防生活方式相关疾病的优势，从2000年开始对年轻人，特别是单身大学生使用IC卡，编制了生活方式相关疾病一级预防体系。1)颈动脉粥样硬化的进展与腹内脂肪积聚有关，2)脂肪肝和高血压在肥胖的年轻人中出现较早(-15%)，3)建立了糖耐量减低的有效筛查方法(0.6%)，结合糖化血红蛋白(HbA1c)对年轻人进行筛查，4)有苗条欲望的女生的BMI与体像不匹配，5)BMI与BMD在女生中的相关性。向所有有帐号的人发放了私人健康检查成绩单。此外，还建立了针对高危人群的随访体系。采用已开发的适合于纵向观察的健康数据监测程序，对人群逼近前后两个等级的BMI进行2年随访，发现适当的BMI有改善的趋势。提示在大学生中采取人群干预与高危干预相结合的方法具有重要意义。

Recently, an increase and younger onset of life-style related diseases have been pointed out. We have compiled the system of primary prevention of life-style related diseases by taking full advantage of our health check-up to prevent life-style related diseases from 1980 and using IC cards from 2000 for young, especially university students starting single life mostly.University students are not interested in their health so high, but they have vague anxiety for it (46%).We obtained some evidences as follows ; 1) the progression of carotid atherosclerosis associated with intra-abdominal fat accumulation even in young, 2) fatty liver and hypertension appear earlier in young with obesity (-15%), 3) efficient screening method of impaired glucose tolerance (0.6%) in combination with HbA1c for young was established, 4) mismatch between BMI and body image in female students with desire of slim, 5) correlation between BMI and BMD using ultrasound in female students.Health education including these evidences and meaning of health check-up as population approach was started since 2003. Private result sheets of health check-up were handed out for all with account. Furthermore, follow-up system for high risk group was established. Using mostly developed health data monitoring program suitable for longitudinal observation, 2 years BMI follow-up study for two grades before and after population approach showed improving tendency of proper BMI. It was suggested that grounded combination of population approach and high risk approach for university students was significant.