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Entrainment of human circadian rhythms by physical exercise : analysis with desynchrony protocol

体育锻炼对人类昼夜节律的影响：使用去同步协议进行分析

基本信息

批准号：
17590197
负责人：
HASHIMOTO Satoko
金额：
$ 2.3万
依托单位：
Hokkaido University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2005
资助国家：
日本
起止时间：
2005 至 2006
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-17590197/
关键词：
Circadian Rhythm Melatonin Human Physical Exercise Phase shits Internal Desynchronization Sleen and Wakefulness Body temnerature rhythm

项目摘要

The purpose of the present study is to elucidate the difference in the effect on the human circadian rhythms between bight light and physical exercise as time cues, the mechanism of the effect of physical exercise and the relation between the effect and strength of exercise(2005) : 15 male subjects were divided into two groups; physical exercise and non-exercise, and stayed in an isolation facilities with illumination of low light intensity for 7 day without knowing the time of day. From the third to 6th of experimental day, the subjects in the exercise group performed physical exercise with a bicycle erometer for 2 hours per day. As a result, the plasma melatonin rhythm showed phase-delay shifts in both groups, and there was no difference in the parameter of melatonin rhythm between two groups. The timing of physical exercise in this experiment was regarded as scheduled in the dead zone of an expected phase response curve of circadian rhythm for physical exercise.(2006) : 7-8 male sub … More jects participated in two experiments, physical exercise and non-exercise. Physical exercise with bicycle ergometer was performed in the subjective evening. As a result, the plasma melatonin rhythm showed phase-delay shifts in a non-exercise experiment, while the melatonin rhythm was not shifted in an exercise experiment. On the other hand, the routine life schedule of 7-8 male subjected was phase-advanced by 8 h in an isolation facility with dim illumination and fixed for 4 days. Meanwhile, the subjects performed physical exercise for 4 hours per day. After that, they were released into free-running conditions where the times of going to bed and get up were decided by the subjects. As a results, the plasma melatonin rhythm was not affected by the phase-advance shift of life schedule, but the sleep-wake rhythm was significantly phase-advanced by physical exercise. Together all, these findings indicate that physical exercise is a potential time cue for the human sleep-wake cycles but not for the circadian rhythms. Less

本研究旨在探讨以光照和体育锻炼为时间线索对人体昼夜节律的影响差异、体育锻炼的作用机制以及运动强度与运动强度的关系（2005）：15名男性受试者分为两组；进行体育锻炼和不进行体育锻炼，并在不知道时间的情况下，在低光强照明的隔离设施中呆了7天。实验第3 ~ 6天，运动组受试者每天用自行车计步器进行2小时的体育锻炼。结果两组血浆褪黑素节律均出现相延迟移位，且两组间褪黑素节律参数无差异。本实验中，体育锻炼的时间被认为安排在体育锻炼生理节律预期相响应曲线的死区。（2006）： 7-8男次。更多的受试者参加了体育锻炼和非运动两个实验。主观晚上用自行车测力器进行体育锻炼。结果表明，在非运动实验中，血浆褪黑素节律出现相延迟偏移，而在运动实验中，褪黑素节律未发生偏移。另一方面，7-8名男性受试者的日常生活时间表在昏暗照明的隔离设施中逐步提前8 h，并固定4天。同时，受试者每天进行4小时的体育锻炼。之后，他们被释放到自由奔跑的环境中，睡觉和起床的时间由受试者决定。结果表明，血浆褪黑素节律不受生活作息时间提前的影响，但运动对睡眠-觉醒节律有显著的提前影响。总之，这些发现表明，体育锻炼是人类睡眠-觉醒周期的潜在时间线索，而不是昼夜节律。少