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Effect of Kampo medicine on cognition and behavior of Alzheimer's disease patinas.

Effect of Kampo medicine on cognition and behavior of Alzheimer's disease patinas.
汉方药物对阿尔茨海默病铜绿认知和行为的影响。
批准号:
16590554
负责人:
ARAI Hiroyuki
金额:
$2.43万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2004
资助国家:
日本
项目状态:
已结题
起止时间:
2004 至 2005

项目摘要

项目成果

ARAI Hiroyuki的其他基金

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中文摘要
翻译
在这项研究中,我们展示了3个主要的发现(循证医学)关于补充和替代的柬埔寨医学1。联合使用多奈哌齐和神药(日本草药)被发现比单独使用每种药物更有益。脑血流量的增加也只在同时接受多奈哌齐和kami-untan-to的患者中观察到。这些结果可能为中西医结合、补充和替代医学的发展提供新的依据。一项随机、安慰剂对照、双盲临床试验显示,中药八味地黄丸治疗8周后,不仅能改善阿尔茨海默病患者的认知功能,还能改善他们的身体活动。2 .使用八味地黄后未发现严重不良事件。目前还没有可靠的治疗方法对路易体痴呆有效。一项观察者盲对照研究表明,中药益肝散有助于减轻痴呆症行为和心理症状的严重程度和频率,如视觉幻觉、妄想和情绪烦躁。值得注意的是,与路易体痴呆相关的视幻觉显著下降,而不产生抗精神病药超敏感性。益肝散不仅改善认知功能。
英文摘要
In this study, we showed 3 major findings (evidenced based medicine) regarding complementary and alternative medicine of Kampo medicine1.A combinatorial use of donepezil and kami-untan-to(Japanese herbal medicine) was found to be more beneficial than each drug alone. An increase in cerebral blood flow also was observed only in the patients who received both donepezil and kami-untan-to. These results may provide a new evidence for integrated medicine of Western/complementary and alternative medicine.2.A randomized, placebo-controlled, double blind clinical trial showed that 8 week treatment by Ba-wei-di-huang wan, a traditional Chinese medicine, wan was found to improve not only cognitive function, but also physical activity in Alzheimer's patients. No serious adverse events were found following use of Ba-wei-di-huang.3.No reliable therapy was known to be beneficial in dementia with Lewy bodies. A observer-blind controlled study showed that Yi-Gan-San, a traditional Chinese medicine, was found to be beneficial in reducing severity and frequency of behavioral and psychological symptoms of dementia such as visual hallucination, delusion and emotional irritability. Notably, it is most notable that visual hallucination associated with dementia with Lewy bodies declined dramatically without producing neuroleptic supersensitivity. Yi-Gan-San improve not only cognitive functions.
期刊论文(74)
专著(0)
科研奖励(0)
会议论文
Caregiver's burden and use of public services among dementia caregivers.
痴呆症护理人员的护理负担和公共服务的使用。
DOI: --
发表时间: 2005
期刊: Geriatr.Gerontol.Internat. (In Press)
影响因子: --
作者: [Tanji H, Ootsuki M, Matsui T, Maruyama M, Nemoto M, Tomita N, Seki T, Iwasaki K, Arai H, Sasaki H.]
通讯作者: Sasaki H.
Effect of Kami-Untan-To on the impairment of leaning nd memory induced by thiamine-deficient feeding in mice.
Kami-Untan-To 对硫胺素缺乏喂养引起的小鼠学习和记忆障碍的影响。
DOI: --
发表时间: 2004
期刊: Neuroscience 125
影响因子: --
作者: [Nakagawasai O, Yamadera F, Iwasaki K, Arai H, Taniguchi R, Tan-no K, Sasaki H, Tadano T.]
通讯作者: Tadano T.
DOI: 10.1016/j.explore.2005.06.007
发表时间: 2005-09-01
期刊: EXPLORE-THE JOURNAL OF SCIENCE AND HEALING
影响因子: 2.4
作者: [Kurusu, Masayuki, Watanabe, Kei, Tamai, Makoto]
通讯作者: Tamai, Makoto
DOI: 10.1291/hypres.27.557
发表时间: 2004-08-01
期刊: HYPERTENSION RESEARCH
影响因子: 5.4
作者: [Hozawa, A, Ebihara, S, Tsuji, I]
通讯作者: Tsuji, I
共 23 条
    Effective utilization of oxidative fermentation mechanism of acetic acid bacteria by engineering of energy metabolism
    • 批准号:
      23658070
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $2.58万
    • 财政年份:
      2011
    • 负责人:
      ARAI Hiroyuki
    • 依托单位:
    Tunable antenna by miniature replica concept
    • 批准号:
      21560389
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.0万
    • 财政年份:
      2009
    • 负责人:
      ARAI Hiroyuki
    • 依托单位:
    Studies on bacterial microaerobic metabolism and its regulation
    • 批准号:
      20380046
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $12.65万
    • 财政年份:
      2008
    • 负责人:
      ARAI Hiroyuki
    • 依托单位:
    Physiological significance of phosphatidylinositol (PI) molecular species in PI signaling
    • 批准号:
      20370045
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $13.06万
    • 财政年份:
      2008
    • 负责人:
      ARAI Hiroyuki
    • 依托单位:
    海外基金