Effect of Kampo medicine on cognition and behavior of Alzheimer's disease patinas.

在这项研究中，我们展示了3个主要的发现（循证医学）关于补充和替代的柬埔寨医学1。联合使用多奈哌齐和神药（日本草药）被发现比单独使用每种药物更有益。脑血流量的增加也只在同时接受多奈哌齐和kami-untan-to的患者中观察到。这些结果可能为中西医结合、补充和替代医学的发展提供新的依据。一项随机、安慰剂对照、双盲临床试验显示，中药八味地黄丸治疗8周后，不仅能改善阿尔茨海默病患者的认知功能，还能改善他们的身体活动。2 .使用八味地黄后未发现严重不良事件。目前还没有可靠的治疗方法对路易体痴呆有效。一项观察者盲对照研究表明，中药益肝散有助于减轻痴呆症行为和心理症状的严重程度和频率，如视觉幻觉、妄想和情绪烦躁。值得注意的是，与路易体痴呆相关的视幻觉显著下降，而不产生抗精神病药超敏感性。益肝散不仅改善认知功能。

In this study, we showed 3 major findings (evidenced based medicine) regarding complementary and alternative medicine of Kampo medicine1.A combinatorial use of donepezil and kami-untan-to(Japanese herbal medicine) was found to be more beneficial than each drug alone. An increase in cerebral blood flow also was observed only in the patients who received both donepezil and kami-untan-to. These results may provide a new evidence for integrated medicine of Western/complementary and alternative medicine.2.A randomized, placebo-controlled, double blind clinical trial showed that 8 week treatment by Ba-wei-di-huang wan, a traditional Chinese medicine, wan was found to improve not only cognitive function, but also physical activity in Alzheimer's patients. No serious adverse events were found following use of Ba-wei-di-huang.3.No reliable therapy was known to be beneficial in dementia with Lewy bodies. A observer-blind controlled study showed that Yi-Gan-San, a traditional Chinese medicine, was found to be beneficial in reducing severity and frequency of behavioral and psychological symptoms of dementia such as visual hallucination, delusion and emotional irritability. Notably, it is most notable that visual hallucination associated with dementia with Lewy bodies declined dramatically without producing neuroleptic supersensitivity. Yi-Gan-San improve not only cognitive functions.